Can the ductus venosus doppler predict the hemoglobinopathies?

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dc.authoridDokuyucu, Recep/0000-0001-7881-8871
dc.authoridDokuyucu, Recep/0000-0001-6837-3477
dc.authoridbenk silfeler, dilek/0000-0002-3533-0523
dc.contributor.authorKarateke, Atilla
dc.contributor.authorSilfeler, Dilek Benk
dc.contributor.authorGungoren, Arif
dc.contributor.authorKurt, Raziye Keskin
dc.contributor.authorOkyay, Ayse Guler
dc.contributor.authorDokuyucu, Recep
dc.contributor.authorUlutas, Turker
dc.date.accessioned2024-09-18T20:26:39Z
dc.date.available2024-09-18T20:26:39Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The aim of our study was to investigate the ductus venosus doppler between 11-13+6 (weekday) in pregnant women with hemoglobinopaties and its relation with fetal outcomes. Material and methods: A total of 100 pregnant women with hemoglobinopathies and 100 healthy pregnant women were included in our study. Ultrasonography (USG) was performed to all pregnant women and the ductus venosus doppler (DVD) flows were evaluated. The results were statistically analyzed. Results: The mean hemoglobin level was significantly lower in hemoglobinopathy group (9.7 +/- 0.7) than control group (10.67 +/- 0.82) (P<0.001). There was a significant relationship between Vmax, Vmin, S/D and reverse 'a' wave in fetuses with hemoglobinopathies. Vmax, Vmin and S/D parameters were higher in the group of hemoglobinopathies (respectively mean value, 31.3 +/- 1.66, 8.90 +/- 0.81, 2.97 +/- 0.49). Reverse 'a' wave was detected especially in all fetuses with sickle cell anemia. There was no significantly relationship between the groups in terms of PI, RI and HR. In a logistic regression analyses, fetal hemoglobinopathy was independently associated with Vmin (beta = 1.07, P = 0.001), S/D (beta = 2.61, P = 0.001) and reverse 'a' wave (beta = 2.46, P = 0.004). Conclusion: Pregnant women with hemoglobinopathies had changed ductus venosus doppler values in compared to normal pregnant women. Maternal anemia may cause this doppler changes. Furthermore all fetuses with sickle cell anemia (n = 5) had abnormal ductus venosus doppler findings. Further studies are needed to investigate the relationship between abnormal ductus venosus doppler findings and fetuses diagnosed with sickle cell anemia.en_US
dc.identifier.endpage4409en_US
dc.identifier.issn1940-5901
dc.identifier.issue3en_US
dc.identifier.pmid26064361en_US
dc.identifier.scopus2-s2.0-84929379019en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage4405en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10465
dc.identifier.volume8en_US
dc.identifier.wosWOS:000355307300166en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHemoglobinopathiesen_US
dc.subjectductus venosus doppleren_US
dc.subjectultrasonographyen_US
dc.titleCan the ductus venosus doppler predict the hemoglobinopathies?en_US
dc.typeArticleen_US

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