Assessment of left ventricular dyssynchrony in dipper and non-dipper hypertension

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dc.contributor.authorKarakas, Mehmet Fatih
dc.contributor.authorBuyukkaya, Eyup
dc.contributor.authorKurt, Mustafa
dc.contributor.authorKarakas, Esra
dc.contributor.authorBuyukkaya, Sule
dc.contributor.authorAkcay, Adnan Burak
dc.contributor.authorSen, Nihat
dc.date.accessioned2024-09-18T20:15:11Z
dc.date.available2024-09-18T20:15:11Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground. Ventricular dyssynchrony is an co-determinant of progression and exacerbation of heart failure (HF). The co-existence of ventricular dyssynchrony with hypertension (HT) and HF were shown, however there is no data regarding the effect of circadian rhythm of blood pressure (BP) on ventricular synchrony. Therefore, we aimed to study the left ventricular synchrony in dipper and non-dipper normotensive and hypertensive participants. Methods. Participants (n = 142) were categorized into four groups as Normotensive-Dipper (NT-D) (n = 40), Normotensive-Non-dipper (NT-ND) (n = 30), Hypertensive-Dipper (HT-D) (n = 38) and Hypertensive-Non-dipper (HT-ND) (n = 34). Left ventricular dyssynchrony was investigated by color-coded tissue Doppler imaging. Results. Non-dippers had higher 24-h and night-time BP both in normotensives and hypertensives. The incidence of ventricular dyssynchrony (a Ts-SD-12 > 34.4 ms) was higher in the hypertensive group (47.2% vs 24.3%, p = 0.005). The frequency of ventricular dyssynchrony was higher in the HT-ND group than the HT-D group (58.8% vs 36.8%, p = 0.05); however, the frequency of ventricular dyssynchrony was similar among the normotensives (26.7% vs 22.5%, p = 0.45). Ts-SD-12 and Ts-12 were higher in NT-ND group than the NT-D group. Conclusions. Non-dipping BP pattern was associated with impaired left ventricular contraction synchrony in both normotensive and hypertensive participants, which may be related with short-and long-term effects of HT on myocardium.en_US
dc.identifier.doi10.3109/08037051.2012.745224
dc.identifier.endpage150en_US
dc.identifier.issn1651-1999
dc.identifier.issue3en_US
dc.identifier.pmid23458091en_US
dc.identifier.scopus2-s2.0-84877776847en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage144en_US
dc.identifier.urihttps://doi.org/10.3109/08037051.2012.745224
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9501
dc.identifier.volume22en_US
dc.identifier.wosWOS:000318807100004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBlood Pressureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiastolic dysfunctionen_US
dc.subjectnon-dipper hypertensionen_US
dc.subjectventricular dyssynchronyen_US
dc.titleAssessment of left ventricular dyssynchrony in dipper and non-dipper hypertensionen_US
dc.typeArticleen_US

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