Fabrication and Characterization of a Multifunctional Coating to Promote the Osteogenic Properties of Orthopedic Implants

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dc.authorid(Gungor) Koc, Serap/0000-0002-4547-0642
dc.authoridOzarslan, Selma/0000-0002-7225-1613
dc.contributor.authorKoc, Serap (Gungor)
dc.contributor.authorBaygar, Tuba
dc.contributor.authorOzarslan, Selma
dc.contributor.authorSarac, Nurdan
dc.contributor.authorUgur, Aysel
dc.date.accessioned2024-09-18T20:27:54Z
dc.date.available2024-09-18T20:27:54Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractTitanium-based alloys are used in orthopedic applications as fixation elements, hard tissue replacements in artificial bones, and dental implants. Despite their wide range of applications, metallic implant defects and failures arise due to inadequate mechanical bonding, postoperative clotting problems, aseptic loosening, and infections. To improve the surface bioactivity and reduce the corrosion rate of the Ti6Al4V alloy, multi-layered coatings (HAp, BG, Cs, and Hep) were applied via electrophoretic deposition (EPD). XRD images showed the presence of HAp within the coating. In vitro investigation: cell line NIH-3T3 fibroblasts were seeded on the non-coated and coated Ti6Al4V substrates, and their cellular behavior was evaluated. The results indicated that the HApBGCsHep coating could enhance the adhesion and proliferation of NIH 3T3 cells. In addition, the potentiodynamic polarization results are compatible with the in vitro outcome.en_US
dc.identifier.doi10.3390/ma16196608
dc.identifier.issn1996-1944
dc.identifier.issue19en_US
dc.identifier.pmid37834746en_US
dc.identifier.scopus2-s2.0-85174040583en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/ma16196608
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10589
dc.identifier.volume16en_US
dc.identifier.wosWOS:001083636900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecthydroxyapatiteen_US
dc.subjectbioglassen_US
dc.subjectchitosanen_US
dc.subjectheparinen_US
dc.subjectTi6Al4V alloyen_US
dc.titleFabrication and Characterization of a Multifunctional Coating to Promote the Osteogenic Properties of Orthopedic Implantsen_US
dc.typeArticleen_US

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