Plasma nesfatin 1 level in patients with first attack psychosis

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dc.contributor.authorSahpolat, M.
dc.contributor.authorAri, M.
dc.date.accessioned2024-09-18T20:25:08Z
dc.date.available2024-09-18T20:25:08Z
dc.date.issued2017
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractOBJECTIVES: This study aimed to investigate the possible relationship between plasma concentrations of nesfatin 1 and first attack psychosis. METHODS: Totally, 32 patients with the first episode psychosis and 33 randomly selected weight- and body mass index-matched healthy volunteers admitted to Mustafa Kemal University, Faculty of Medicine, Training and Research Hospital, Psychiatry outpatient clinic were included. Healthy control subjects were matched in terms of weight and body mass index (BMI). The Positive and Negative Syndrome Scale (PANNS) was applied to the patient group. The enzyme-linked immunosorbent assay (ELISA) method was used to measure plasma nesfatin 1 levels. RESULTS: The mean nesfatin 1 level was lower in the patients with the first attack psychosis (0.60 +/- 1.00 ng/mL) than in the control group (0.75 +/- 1.07 ng/mL).However it did not reach statistical significance (t = 0.567, p = 0.573). There was no statistically significant correlation between plasma nesfatin 1 levels and total PANNS scores in the patient group (r = 0.262, p = 0.148). CONCLUSION: Our study was the first to investigate the nesfatin 1 levels in patients with the first episode psychosis. Based on our study results, nesfatin 1 might be related to some central nervous system pathologies, including the severity of a psychiatric disorder; however, further large-scale studies are required to establish a conclusion (Tab. 1, Ref. 21). Text in PDF www.elis.sk.en_US
dc.identifier.doi10.4149/BLL_2017_015
dc.identifier.endpage79en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue2en_US
dc.identifier.pmid28814086en_US
dc.identifier.scopus2-s2.0-85014901822en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage77en_US
dc.identifier.urihttps://doi.org/10.4149/BLL_2017_015
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10089
dc.identifier.volume118en_US
dc.identifier.wosWOS:000395357800002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherComenius Univen_US
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectfirst attack psychosisen_US
dc.subjectplasma nesfatin 1en_US
dc.subjectbody mass indexen_US
dc.titlePlasma nesfatin 1 level in patients with first attack psychosisen_US
dc.typeArticleen_US

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