Prognostic nutritional index predicts in-hospital mortality in patients with acute Stanford type A aortic dissection

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dc.contributor.authorKeskin, Hasan Attila
dc.contributor.authorKurtul, Alparslan
dc.contributor.authorEsenboga, Kerim
dc.contributor.authorCicek, Mustafa Cuneyt
dc.contributor.authorKatircioglu, Salih Fehmi
dc.date.accessioned2024-09-18T19:50:19Z
dc.date.available2024-09-18T19:50:19Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: Acute Stanford type A aortic dissection (ATAAD) is a life-threatening medical emergency. The aim of this study was to investigate the clinical significance of the prognostic nutritional index (PNI) as a novel inflammatory marker for ATAAD patients undergoing surgical repair. Methods: We retrospectively examined the medical records of 151 ATAAD patients who treated surgically. Patients were divided into two groups (survival and death) and these groups were compared with respect to clinical and laboratory parameters. The PNI was calculated as 10 x serum albumin (g/dL) + 0.005 x total lymphocyte count (per mm(3)). Logistic regression analyses were performed to identify the risk factors of in-hospital mortality. Results: The mean age of the study cohort was 61 +/- 12 years, 99 (65.6%) were males, and 35 (23.2%) patients died during the hospital stay. The PNI levels were significantly lower in death group compared with survival group (32.80 +/- 4.90 vs. 37.94 +/- 5.42, p < 0.001). Multivariate analysis showed that the PNI (OR: 0.795, p = 0.005), age (odds ratio [OR]: 1.085, p = 0.034), operating time (OR: 1.660, p = 0.042), and D-dimer (OR: 1.002, p = 0.001) independently predicted in-hospital mortality. The calculated cutoff value of the PNI was 33.01. Conclusion: Lower PNI values are independently associated with in-hospital mortality in ATAAD. The PNI may be a useful tool for predicting the early mortality of ATAAD patients after surgical repair.en_US
dc.identifier.doi10.1177/0267659120961937
dc.identifier.endpage716en_US
dc.identifier.issn0267-6591
dc.identifier.issn1477-111X
dc.identifier.issue7en_US
dc.identifier.pmid33070761en_US
dc.identifier.scopus2-s2.0-85092718997en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage710en_US
dc.identifier.urihttps://doi.org/10.1177/0267659120961937
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7349
dc.identifier.volume36en_US
dc.identifier.wosWOS:000580957400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofPerfusion-Uken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectacute aortic dissectionen_US
dc.subjectin-hospital mortalityen_US
dc.subjectrisk stratificationen_US
dc.subjectprognostic nutritional indexen_US
dc.titlePrognostic nutritional index predicts in-hospital mortality in patients with acute Stanford type A aortic dissectionen_US
dc.typeArticleen_US

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