External validation of the TOHO. score and derivation of the modified TOHO. score for predicting stone-free status after flexible ureteroscopy in ureteral and renal stones

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dc.authoridDanacioglu, Yavuz Onur/0000-0002-3170-062X
dc.authoridSeker, Kamil Gokhan/0000-0003-4449-9037
dc.authoridSoytas, Mustafa/0000-0002-3474-3510
dc.authoridyarimoglu, serkan/0000-0002-3236-9422
dc.authoridKoras, omer/0000-0001-9749-5254
dc.authoridFakir, Ali Emre/0000-0001-6828-1986
dc.contributor.authorPolat, Salih
dc.contributor.authorDanacioglu, Yavuz Onur
dc.contributor.authorSoytas, Mustafa
dc.contributor.authorYarimoglu, Serkan
dc.contributor.authorKoras, Omer
dc.contributor.authorFakir, Ali Emre
dc.contributor.authorSeker, Kamil Gokhan
dc.date.accessioned2024-09-18T21:05:14Z
dc.date.available2024-09-18T21:05:14Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective The T.O.HO. scoring system was developed to predict stone-free status after flexible ureterenoscopy (fURS) lithotripsy applied for ureter and renal stones. This study aimed to perform the external validation of the T.O.HO. score in the Turkish population and propose a modification for this system. Material methods Patients who underwent fURS for kidney and ureteral stones between January 2017 and January 2020 were retrospectively analysed. The patient and stone characteristics and perioperative findings were noted. The T.O.HO. score was externally validated and compared with the STONE score. Stone-free parameters were evaluated with the multivariate analysis. Based on the results of this analysis, the T.O.HO. score was modified and internally validated. Results A total of 621 patients were included in the study. The stone-free rate was determined as 79.8% (496/621) after fURS. The regression analysis showed that stone area had better predictive power than stone diameter (P = .025). Lower pole (reference), middle pole [odds ratio (OR) = 0.492 P = .016] and middle ureteral (OR = 0.227, P = .024) localisations, stone density (OR = 1.001, P < .001), and stone volume (OR = 1.008, P < .001) were determined as independent predictive markers for stone-free status. Based on the effect size of the stone surface area in the nomogram, stone volume was divided into five categories, at 1-point intervals. The AUC values of the T.O.HO., STONE, and modified T.O.HO. score in predicting stone-free status were calculated as 0.758, 0.634, and 0.821, respectively. The modified T.O.HO. created by adding stone volume was statistically significantly superior to the original version (ROC curve comparison, P < .001). Conclusion The T.O.HO. score effectively predicted stone-free status after fURS. However, modified T.O.HO. SS showed the best predictive performance compared with original T.O.HO. SS.en_US
dc.identifier.doi10.1111/ijcp.14653
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.pmid34320257en_US
dc.identifier.scopus2-s2.0-85111781163en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.14653
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13462
dc.identifier.wosWOS:000680932000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRetrograde Intrarenal Surgeryen_US
dc.subjectManagementen_US
dc.subjectNomogramen_US
dc.subjectComplexityen_US
dc.subjectSystemen_US
dc.titleExternal validation of the TOHO. score and derivation of the modified TOHO. score for predicting stone-free status after flexible ureteroscopy in ureteral and renal stonesen_US
dc.typeArticleen_US

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