Prolidase activity and oxidative stress in patients with schizophrenia: A preliminary study

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dc.authoridSelek, Salih/0000-0001-5197-5682
dc.contributor.authorBahceci, Bulent
dc.contributor.authorBagcioglu, Erman
dc.contributor.authorKokacya, Mehmet Hanefi
dc.contributor.authorDilek, Aziz Ramazan
dc.contributor.authorBahceci, Ilkay
dc.contributor.authorSelek, Salih
dc.date.accessioned2024-09-18T20:55:29Z
dc.date.available2024-09-18T20:55:29Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: To determine whether serum prolidase levels are associated with the etiopathogenesis of schizophrenia. Methods: The study was conducted at the psychiatry outpatient clinics of the University Hospitals of Recep Tayyip Erdogan and Afyonkocatepe in spring 2013. It comprised patients with schizophrenia who were consecutively recruited from the Psychiatry outpatient clinics of the hospital. An equal number of healthy individuals were recruited from the community. Each patient underwent a detailed diagnostic evaluation by psychiatry residents by using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV. Serum prolidase activity and oxidative parameters were measured in patient and control groups. The severity of psychotic symptoms was assessed using the positive and negative syndrome scale. SPSS 16 was used for statitistical analysis. Results: There were 30 subjects in each group, with 18(60%)females among the patients and 21(70%) among the controls. Serum prolidase level was significantly higher in schizophrenia patients compared to the controls (p<0.001). Total Oxidative Stress and Oxidative Stress Index parameters were found to be significantly different between the patients and the controls (p=0.024 and pen_US
dc.identifier.endpage135en_US
dc.identifier.issn0030-9982
dc.identifier.issue2en_US
dc.identifier.pmid25842545en_US
dc.identifier.scopus2-s2.0-84928237680en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage131en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11849
dc.identifier.volume65en_US
dc.identifier.wosWOS:000349195700005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPakistan Medical Assocen_US
dc.relation.ispartofJournal of The Pakistan Medical Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProlidase activityen_US
dc.subjectSchizophreniaen_US
dc.subjectProlineen_US
dc.subjectGlutamaten_US
dc.titleProlidase activity and oxidative stress in patients with schizophrenia: A preliminary studyen_US
dc.typeArticleen_US

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