CHANGES IN THE OXIDATIVE STATUS AND SERUM TRACE ELEMENT LEVELS IN DOGS WITH MAMMARY TUMOURS

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dc.contributor.authorAskar, T. K.
dc.contributor.authorSalmanoglu, B.
dc.contributor.authorSalmanoglu, R.
dc.contributor.authorErkal, N.
dc.contributor.authorBeskaya, A.
dc.date.accessioned2024-09-18T20:15:18Z
dc.date.available2024-09-18T20:15:18Z
dc.date.issued2009
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe purpose of the study was to evaluate the changes in oxidative status and serum trace element levels by determining the concentrations of malondialdehyde (MDA), nitric oxide (NO), ascorbic acid, and certain trace elements. The study included 15 clinically healthy female dogs and 15 dogs with malignant mammary tumour Blood samples were taken from the jugular vein of the patient dogs just before the surgical treatment. The patients exhibited a significant increase in MDA (P<0.001), NO (P<0.001), Fe (P<0.001), and Cu (P<0.01) levels and a significant decrease in levels of ascorbic acid (P<0.001) and Zn (P<0.01). A strong correlation was observed in the patient group for ascorbic acid and Fe (r=-0.87) concentration, but there was a weak correlation between ascorbic acid and Cu (r=-0.69), and Zn (r=0.49) concentrations. Also there was a strong correlation between Zn and MDA (r=-0.84) concentrations, indicating oxidative stress. The results suggest that ROS generated by trace elements, like Fe and Cu may cause the mammary tumours.en_US
dc.identifier.doi10.2298/AVB0904405A
dc.identifier.endpage411en_US
dc.identifier.issn0567-8315
dc.identifier.issn1820-7448
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-70349966104en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage405en_US
dc.identifier.urihttps://doi.org/10.2298/AVB0904405A
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9560
dc.identifier.volume59en_US
dc.identifier.wosWOS:000270452700007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDe Gruyter Poland Sp Zooen_US
dc.relation.ispartofActa Veterinaria-Beograden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectdogen_US
dc.subjectmammary tumouren_US
dc.subjectoxidative stressen_US
dc.subjecttrace elementsen_US
dc.titleCHANGES IN THE OXIDATIVE STATUS AND SERUM TRACE ELEMENT LEVELS IN DOGS WITH MAMMARY TUMOURSen_US
dc.typeArticleen_US

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