Stroke in children with sickle cell anemia

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dc.authorscopusid8944423300
dc.authorscopusid8944423400
dc.authorscopusid6507419304
dc.contributor.authorMelek, Ismet M.
dc.contributor.authorDuman, Taşkin
dc.contributor.authorGali, Edip
dc.date.accessioned2024-09-19T15:45:37Z
dc.date.available2024-09-19T15:45:37Z
dc.date.issued2004
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPatient groups at high risk with respect to cerebrovascular disease has a particular importance in terms of etiological and clinic evaluations. Sickle cell anemia has an important place in the etiology of patients who have had stroke before the age of 20. Among the risk factor of cerebrovascular diseases occurring during childhood, sickle cell anemia is the second important cause following the congenital heart diseases. The probability of a patient with sickle cell anemia to have cerebral infarction is 250 times higher when compared to those who don't have this disease at same age. Those who are born in Hatay forms the 17.49% of the all hemoglobinopathy cases reported in Turkey. In this study, the data on stroke obtained from 506 cases by hemoglobin electrophoresis since 1994 in Hatay, where 10.5% of the population is the carrier, was reported. Of the cases, 403 (79,6%), 99 (19,6%), 2 (0,4%) and 2 (0,4%) were HbSS, HbSS+Thalessemia, HbSD and HbSE, respectively. During a period of 10 year, 5 patients had stroke. Among them, the youngest one was 3 yr old while the oldest one was 15 yr old. The data on hemopatolgical parameters and on clinical and etiological were investigated. Being an autosomal recessive disease and arising from the mutation of hemoglobin beta gene, sickle cell anemia is considered to be a high risk factor for stroke besides the hematological features. In the regions where gene carriers are densely populated, studies on early diagnosis and monitoring appears to be highly important in the detection and prevention of childhood strokes.en_US
dc.identifier.endpage128en_US
dc.identifier.issn1301-1375
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-13644251485en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage121en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14804
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkish Society of Cerebrovascular Diseasesen_US
dc.relation.ispartofTurk Beyin Damar Hastaliklar Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComplicationen_US
dc.subjectNeurologicen_US
dc.subjectRisk factorsen_US
dc.subjectSickle cell anemiaen_US
dc.subjectStrokeen_US
dc.titleStroke in children with sickle cell anemiaen_US
dc.title.alternativeOrak hücreli? anemi?li? çocuklarda i?nmeen_US
dc.typeArticleen_US

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