Sickle cell diseases and ileus

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dc.authoridUgur, Mustafa/0000-0002-5922-2367
dc.contributor.authorHelvaci, Mehmet Rami
dc.contributor.authorAydogan, Akin
dc.contributor.authorAkkucuk, Seckin
dc.contributor.authorOruc, Cem
dc.contributor.authorUgur, Mustafa
dc.date.accessioned2024-09-18T20:57:02Z
dc.date.available2024-09-18T20:57:02Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: We tried to understand whether or not there is an increased incidence of ileus in patients with sickle cell diseases (SCDs). Methods: All cases with SCDs were taken into the study. Results: The study included 325 patients (160 females). The mean ages were similar in both sexes (29.3 versus 29.8 years in females and males, respectively, p > 0.05). Incidence of ileus was higher in males, significantly (3.6% versus 1.2%, p < 0.01). All of the ileus cases were able to be treated with simple and repeated red blood cell (RBC) transfusions without any surgical procedure. Smoking was higher in males, too (21.8% versus 6.2%, p < 0.001). The mean hematocrit value was also higher in males, significantly (24.4% versus 23.0%, p = 0.016). RBC units transfused, digital clubbing, leg ulcers, pulmonary hypertension, chronic obstructive pulmonary disease, coronary heart disease, and chronic renal disease were all higher in males, too (p < 0.05 for all). On the other hand, although the general mortality, white blood cell and platelet counts of peripheric blood, painful crises per year, rheumatic heart disease, avascular necrosis of bone, cirrhosis, and stroke were all higher in males, the differences were nonsignificant probably due to the small sample sizes of the groups (p > 0.05 for all). Conclusion: Although the relatively young mean ages of the patients with SCDs, the very high incidences of ileus are probably due to the strong atherosclerotic and obstructive natures of the two pathologies, and ileus should be treated with simple and repeated RBC transfusions to restore bowel perfusion in such patients.en_US
dc.identifier.endpage2876en_US
dc.identifier.issn1940-5901
dc.identifier.issue9en_US
dc.identifier.pmid25356151en_US
dc.identifier.scopus2-s2.0-84907854946en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage2871en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12252
dc.identifier.volume7en_US
dc.identifier.wosWOS:000345121000060en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSickle cell diseasesen_US
dc.subjectileusen_US
dc.subjectatherosclerosisen_US
dc.subjectchronic endothelial damageen_US
dc.titleSickle cell diseases and ileusen_US
dc.typeArticleen_US

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