Immunohistochemical study on roe deer haemal nodes

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dc.contributor.authorBozkurt, Y. Akaydin
dc.contributor.authorSari, E. Karadag
dc.contributor.authorKabak, M.
dc.date.accessioned2024-09-18T20:08:07Z
dc.date.available2024-09-18T20:08:07Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to investigate the immunohistochemical characteristics of the haemal nodes located in the abdominal and thoracic cavities in roe deer (Capreolus capreolus). Materials and methods: In this study, 2 adult male and 2 adult female roe deers in addition to 2 roe deer foetuses at the late foetal stages were used. The avidin-biotin-peroxidase technique was applied to anti-CD3, anti-CD79 alpha cy, anti-macrophage, anti-S100 primary antibodies. Results: Positive results were gained for all the antibodies used. Many CD3 positive T-lymphocytes were seen in the lymphoid tissue areas of the foetal haemal nodes, in the germinal centre of the lymph follicles of the adult haemal nodes and in their lymphatic cords. CD79 alpha cy positive cells were less in number while S-100 protein was positive in both lymph follicles and in sinuses of the adult haemal nodes. In foetal haemal nodes, cells positive for S-100 protein were more prevalent in the sinuses. For the MAC387 primary antibody, there were positive macrophages seen in the capsule and trabeculae of the haemal nodes, located denser in males. Macrophage cells in the lymphoid structures and granulocytes in the sinuses of the haemal nodes of both adults and foetuses were positive for MAC387. Conclusions: This study is the first one to define the detailed structural features immunohistochemically in the haemal nodes of the roe deer. Even its concluded that the results were similar with the other ruminants, it's also pointed out that there are certain differences among the foetal, adult male and female haemal nodes of the roe deeren_US
dc.identifier.doi10.5603/FM.a2017.0103
dc.identifier.endpage271en_US
dc.identifier.issn0015-5659
dc.identifier.issn1644-3284
dc.identifier.issue2en_US
dc.identifier.pmid29131281en_US
dc.identifier.scopus2-s2.0-85048380769en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage266en_US
dc.identifier.urihttps://doi.org/10.5603/FM.a2017.0103
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8647
dc.identifier.volume77en_US
dc.identifier.wosWOS:000436178400010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofFolia Morphologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCD3en_US
dc.subjectCD79 alpha cyen_US
dc.subjectmacrophageen_US
dc.subjectS-100 proteinen_US
dc.subjectimmunohistochemistryen_US
dc.subjecthaemal nodeen_US
dc.subjectroe deeren_US
dc.titleImmunohistochemical study on roe deer haemal nodesen_US
dc.typeArticleen_US

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