The relationship between low thiol levels and major adverse cardiovascular events after primary percutaneous coronary intervention in patients with STEMI

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dc.authoridKOCA, HASAN/0000-0002-6232-4567
dc.authoridSen, Omer/0000-0002-6782-2899
dc.contributor.authorAkkus, Oguz
dc.contributor.authorTopuz, Mustafa
dc.contributor.authorKoca, Hasan
dc.contributor.authorHarbalioglu, Hazar
dc.contributor.authorKaypakli, Onur
dc.contributor.authorKaplan, Mehmet
dc.contributor.authorSen, Omer
dc.date.accessioned2024-09-18T21:06:43Z
dc.date.available2024-09-18T21:06:43Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractOjective: The aim of this study was to investigate whether low thiol levels are associated with peri-procedural factors during primary percutaneous coronary intervention (pPCI) upon admission with ST-segment elevation myocardial infarction (STEMI), and the prognostic value at 6-month follow-up. Methods: A total of 241 consecutive acute STEMI patients who underwent pPCI and a control group of 67 individuals with a normal coronary angiography were enrolled in the study. Result: While age, contrast-induced nephropathy, N-terminal prohormone of brain natriuretic peptide (NT-proBNP), stent length, and creatinine were related to native thiol, NT-proBNP, contrast-induced nephropathy, and creatinine were related to total thiol. NT-proBNP was also related to the disulphide level. The left ventricular ejection fraction (LVEF) and the levels of native thiol, total thiol, low-density lipoprotein, and serum albumin were found to be independent predictors of major adverse cardiovascular events (MACEs) during 6 months of follow-up. Conclusion: Initial lower native thiol, total thiol, LVEF, LDL, and serum albumin may be used to identify patients with an increased long-term risk of unfavorable cardiac events in case of STEMI.en_US
dc.identifier.doi10.5543/tkda.2018.82668
dc.identifier.endpage259en_US
dc.identifier.issn1016-5169
dc.identifier.issue4en_US
dc.identifier.pmid29853692en_US
dc.identifier.startpage248en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2018.82668
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13778
dc.identifier.volume46en_US
dc.identifier.wosWOS:000435148100003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElevation Myocardial-Infarctionen_US
dc.subjectOxidative Stressen_US
dc.subjectThiol/Disulphide Homeostasisen_US
dc.subjectNo-Reflowen_US
dc.subjectSyntax Scoreen_US
dc.subjectHuman Plasmaen_US
dc.subjectMarkeren_US
dc.subjectRisken_US
dc.subjectAngiographyen_US
dc.subjectAlbuminen_US
dc.titleThe relationship between low thiol levels and major adverse cardiovascular events after primary percutaneous coronary intervention in patients with STEMIen_US
dc.typeArticleen_US

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