Subclinical atrial fibrillation frequency and associated parameters in patients with cardiac resynchronization therapy

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dc.authoridKURT, IBRAHIM HALIL/0000-0001-5007-2246
dc.contributor.authorUgurlu, Mehmet
dc.contributor.authorKaypakli, Onur
dc.contributor.authorSahin, Durmus Yildiray
dc.contributor.authorIcen, Yahya Kemal
dc.contributor.authorKurt, Ibrahim Halil
dc.contributor.authorKoc, Mevlut
dc.date.accessioned2024-09-18T20:06:31Z
dc.date.available2024-09-18T20:06:31Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe presence of subclinical atrial fibrillation (SCAF) is relevant to issues such as the risk of stroke and the necessity of anticoagulant use in patients with cardiac resynchronization therapy (CRT). Our study aimed to investigate SCAF frequency and associated parameters in patients with CRT. One hundred ninety-one patients with CRT (77 females, 114 males, mean age 65.9 +/- 9.8) were included in the study. Atrial high-rate episodes detected by the device, atrial electrode impedance, P-wave sense amplitude, and atrial lead threshold values were measured during pacemaker controls. SCAF was defined as asymptomatic atrial high-rate episodes (AHRE) longer than 6 min and shorter than 24 h. Patients were divided into two groups as with and without SCAF. SCAF was detected in 44 (23.2%) of 191 patients with CRT. Age, sex, weight, aortic end-systolic diameter, left atrium (LA) diameter, left bundle branch block morphology, CHA(2)DS(2)-VASc score, and right atrium thresholds were associated with SCAF. In multivariate regression analysis, CHA(2)DS(2)-VASc score, LA diameter, and atrial threshold values were found to be independent predictors of SCAF occurrence. According to this analysis, every 1 point increase in CHA(2)DS(2)-VASc score, every 1 mm increase in LA diameter, and every 0.1 V increase in atrial threshold increased the risk of SCAF by 32.5, 59.6, and 14.6%, respectively. In the ROC analysis, the area under the curve (AUC) was 0.870, 0.638, and 0,652 for LA diameter, CHA2DS2-VASc score, and atrial lead threshold, respectively (p < 0.05, for all). The cut-off values were 34 mm, 3, and 0.6 V for LA diameter, CHA2DS2-VASc score, and atrial lead threshold, respectively. Patients with CRT have significantly higher frequency of SCAF than the normal population. CHA(2)DS(2)-VASc score, LA diameter, and atrial threshold values were considered to be useful and easily applicable parameters in identifying the patients to develop SCAF.en_US
dc.identifier.doi10.1007/s10840-018-0385-4
dc.identifier.endpage223en_US
dc.identifier.issn1383-875X
dc.identifier.issn1572-8595
dc.identifier.issue2en_US
dc.identifier.pmid29804173en_US
dc.identifier.scopus2-s2.0-85047406913en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://doi.org/10.1007/s10840-018-0385-4
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8563
dc.identifier.volume52en_US
dc.identifier.wosWOS:000437464000013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Interventional Cardiac Electrophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac resynchronization therapyen_US
dc.subjectSubclinical atrial fibrillationen_US
dc.subjectHeart failureen_US
dc.titleSubclinical atrial fibrillation frequency and associated parameters in patients with cardiac resynchronization therapyen_US
dc.typeArticleen_US

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