Calcium Homeostasis During Attack and Remission in Patients With Idiopathic Benign Paroxysmal Positional Vertigo

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dc.authoridKahraman, Serif Samil/0000-0003-3115-8823
dc.contributor.authorKahraman, Serif Samil
dc.contributor.authorOzcan, Oguzhan
dc.contributor.authorArli, Cengiz
dc.contributor.authorUstun, Ihsan
dc.contributor.authorErduran, Rana
dc.contributor.authorAkoglu, Ertap
dc.contributor.authorGokce, Cumali
dc.date.accessioned2024-09-18T20:02:44Z
dc.date.available2024-09-18T20:02:44Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective:To evaluate changes in calcium metabolism in patients with idiopathic benign paroxysmal positional vertigo (BPPV) on initial presentation and at the follow-up visit.Subjects and Methods:The study comprised a total of 31 patients aged greater than 18 years who presented at the otorhinolaryngology outpatient clinic of our hospital, newly diagnosed as idiopathic BPPV based on the history compatible with BPPV and positive provocative maneuver (either Dix-Hallpike or Roll test). The first blood sample was obtained on the day of initial presentation when the patient was found to have active unilateral BPPV. After 6 months, a blood sample was again drawn in accordance with the procedure. Blood samples were analyzed for data on 25-hydroxyvitamin D (25(OH)-D), total calcium, parathormone and ionized calcium on initial presentation, and at the follow-up visit.Results:The patients comprised 20 (64.5%) women and 11 (35.5%) men with a mean age of 49.78 years (range, 23-75 years). During an attack a higher prevalence of decreased serum Vitamin D is less than 20ng/ml, was determined (93.5% versus 38.7%). There were statistical differences between the Vitamin D values, parathormone, and corrected by pH ionized calcium in both periods (p<0.05).Conclusion:A statistically significant association was determined between Vitamin D and calcium metabolism in patients with idiopathic BPPV. It can be considered that Vitamin D deficiency and decreased ionized Ca level may be a risk for BPPV, not only in patients with osteoporosis but also in all patients. Very low levels of 25(OH)-D seem to be associated with recurrence of BPPV. The recurrences might possibly be prevented with supplementary Vitamin D especially in those with recurrent idiopathic BPPV but further studies would be necessary to determine this.en_US
dc.identifier.doi10.1097/MAO.0000000000001167
dc.identifier.endpage1392en_US
dc.identifier.issn1531-7129
dc.identifier.issn1537-4505
dc.identifier.issue9en_US
dc.identifier.pmid27525708en_US
dc.identifier.scopus2-s2.0-84981703794en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1388en_US
dc.identifier.urihttps://doi.org/10.1097/MAO.0000000000001167
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8000
dc.identifier.volume37en_US
dc.identifier.wosWOS:000384464300044en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofOtology & Neurotologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAttacken_US
dc.subjectBPPVen_US
dc.subjectCalciumen_US
dc.subjectHomeostasisen_US
dc.subjectPTHen_US
dc.subjectRemissionen_US
dc.subjectVitamin Den_US
dc.titleCalcium Homeostasis During Attack and Remission in Patients With Idiopathic Benign Paroxysmal Positional Vertigoen_US
dc.typeArticleen_US

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