Relationship between Serum Resistin and Lipid Levels in Patients with Psoriasis

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dc.contributor.authorYilmaz, Nigar
dc.contributor.authorUlutas, Kemal Turker
dc.contributor.authorDogramaci, A. Cigdem
dc.contributor.authorInan, M. Ugur
dc.contributor.authorYuksel, Rana
dc.contributor.authorCan, Yesim
dc.date.accessioned2024-09-18T20:55:32Z
dc.date.available2024-09-18T20:55:32Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: Psoriasis is inflammatory skin disease which has increased risk of cardiovascular disease. The etiology is unknown, yet. In cardiovascular disease, resistin which is secreted from adipose tissue, was found correlated with the levels of total cholesterol and LDL. In our study, we aimed to study the relation of serum resistin and lipid levels in patients with psoriasis and correlation of Psoriasis Area and Severity Index (PASI). Material and Methods: In Mustafa Kemal University, Faculty of Medicine, Department of Dermatology, thirty-seven healthy subjects (group I) and thirty-four patients with psoriasis (group II) were enrolled for two groups. The age, gender, blood pressure, body mass index (BMI) and PASI were determined. The level of resistin and lipid profile were studied in serum. Results: The level of resistin in patients with psoriasis (12,3 +/- 3,0 ng/ml) was found increased compared with healthy subjects (6,4 +/- 2,3 ng/ml) (p=0.001). The level of total cholesterol and LDL were increased in patients with psoriasis compared with healthy subjects, respectively (189 +/- 43 mg/dl; 129 +/- 31 mg/dl) (p<0,05; p=0,01). The level of resistin was determined correlated positively with LDL (r=0,306). The level of resistin was found strong correlated positively with PASI (r=0,669). Conclusion: The high risk of cardiovascular disease in patients with psoriasis is known. In our study, the levels of resistin, total cholesterol, LDL which increase in cardiovascular disease, was found increased in patients with psoriasis and correlated with PASI. The level of resistin may be increased with increasing severity of the disease, so that it is thought to be significant determining like the lipid profile in patients with psoriasis.en_US
dc.identifier.endpage287en_US
dc.identifier.issn0250-5150
dc.identifier.issue2en_US
dc.identifier.startpage282en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11901
dc.identifier.volume40en_US
dc.identifier.wosWOS:000360663100013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.relation.ispartofCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPsoriasisen_US
dc.subjectresistinen_US
dc.subjectlipidsen_US
dc.titleRelationship between Serum Resistin and Lipid Levels in Patients with Psoriasisen_US
dc.typeArticleen_US

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