Microbiological Diagnosis of Prosthetic Joint Infections

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dc.contributor.authorOzer, Burcin
dc.date.accessioned2024-09-18T20:32:51Z
dc.date.available2024-09-18T20:32:51Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractProsthetic joint infections (PJI) are the most important complication of joint replacement surgery. Diagnosis of PJI should be made with a multidisciplinary approach. Microbiological diagnostic methods must be used to isolate the causative microorganisms and to determine the antimicrobial susceptibility of these microorganisms. Microbiological methods used in preoperative diagnosis are blood culture, leukocyte count and type in synovial fluid and culture of synovial fluid. Those used in intraoperative diagnosis are cultures of abscesses, synovial fluid, soft tissue and bones located in and around prosthesis taken during the surgery. Other microbiological methods used in diagnosis of Pi's are microcalorimetry, matrix assisted lazer desorption/ionization-time of flight mass spectrometry, homogenization of tissue samples with glass beads, fluorescent in situ hybridization, synovial biomarkers, enzymatic template generation and amplification. Also, various molecular methods such as 16S rRNA sequencing analysis and polymerase chain reaction methods can be used for diagnosis of PJI. The aim of this review was to discuss the microbiological diagnostic methods of PJI in the light of current literatures.en_US
dc.identifier.doi10.4274/mjima.galenos.2021.2020.24
dc.identifier.issn2147-673X
dc.identifier.scopus2-s2.0-85111488604en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.urihttps://doi.org/10.4274/mjima.galenos.2021.2020.24
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11165
dc.identifier.volume10en_US
dc.identifier.wosWOS:000693863100005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofMediterranean Journal of Infection Microbes and Antimicrobialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMicrobiologyen_US
dc.subjectprosthesisen_US
dc.subjectjoint infectionsen_US
dc.subjectdiagnosisen_US
dc.titleMicrobiological Diagnosis of Prosthetic Joint Infectionsen_US
dc.typeReview Articleen_US

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