Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department.

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dc.contributor.authorYaman, Fatih Nazmi
dc.contributor.authorCivelek, Birol
dc.contributor.authorYavuz, Bunyamin
dc.contributor.authorYilmaz, Mustafa
dc.contributor.authorAtescelik, Metin
dc.contributor.authorSahan, Mustafa
dc.contributor.authorGoktekin, Mehmet Cagri
dc.date.accessioned2024-09-18T20:02:44Z
dc.date.available2024-09-18T20:02:44Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractObjective: To evaluate the relationship between CHA(2)DS(2)-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF). Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA(2)DS(2)-VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA(2)DS(2)-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA(2)DS(2)-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA(2)DS(2)-VASc score being >= 2. The mean age of patients was 68 +/- 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA(2)DS(2)-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001). Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA(2)DS(2)-VASc and these markers in high-risk patients with CHA(2)DS(2)-VASc score >= 2.en_US
dc.identifier.endpage590en_US
dc.identifier.issn0970-938X
dc.identifier.issn0976-1683
dc.identifier.issue3en_US
dc.identifier.startpage586en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7996
dc.identifier.volume27en_US
dc.identifier.wosWOS:000388456100002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAllied Acaden_US
dc.relation.ispartofBiomedical Research-Indiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtrial fibrillationen_US
dc.subjectBNPen_US
dc.subjectCHA(2)DS(2)-VASc scoreen_US
dc.subjectD-Dimeren_US
dc.subjecths-CRPen_US
dc.subjectvWFen_US
dc.titleEvaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department.en_US
dc.typeArticleen_US

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