Autonomic Nervous System Dysfunction in Lifelong Premature Ejaculation: Analysis of Heart Rate Variability

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dc.contributor.authorZorba, Orhan Unal
dc.contributor.authorCicek, Yuksel
dc.contributor.authorUzun, Hakki
dc.contributor.authorCetinkaya, Mehmet
dc.contributor.authorOnem, Kadir
dc.contributor.authorRifaioglu, Mehmet Murat
dc.date.accessioned2024-09-18T21:03:11Z
dc.date.available2024-09-18T21:03:11Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractOBJECTIVE To identify autonomic nervous dysfunction in patients with lifelong premature ejaculation. METHODS The study participants were 25 men with lifelong premature ejaculation and 25 healthy controls. The parameters of 24-hour heart rate variability that are influenced by the autonomic nervous system were compared between the men with lifelong premature ejaculation and the healthy controls. RESULTS The laboratory results of all patients were within normal limits, and no significant differences were found between the patients and the controls in age, body weight, and body mass index. A low-frequency signal that is influenced by the sympathetic system was increased in the patients (P = .026). Furthermore, a high-frequency signal that is influenced by the parasympathetic system was decreased in the patients (P = .011). Finally, the low frequency-to-high frequency ratio, an indicator of the balance between the two components of the autonomic nervous system, was increased in the patients (P = .002). CONCLUSION To our knowledge, no study has investigated the influence of the autonomic nervous system on 24-hour heart rate variability in premature ejaculation. In the present study, sympathetic activity was increased in men with lifelong premature ejaculation; this overactivity might lead to lifelong premature ejaculation. Additional studies are required to reveal the possible alteration of the autonomic nervous system in premature ejaculation. UROLOGY 80: 1283-1286, 2012. (c) 2012 Elsevier Inc.en_US
dc.identifier.doi10.1016/j.urology.2012.08.029
dc.identifier.endpage1286en_US
dc.identifier.issn0090-4295
dc.identifier.issn1527-9995
dc.identifier.issue6en_US
dc.identifier.pmid23102443en_US
dc.identifier.scopus2-s2.0-84870691771en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1283en_US
dc.identifier.urihttps://doi.org/10.1016/j.urology.2012.08.029
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13295
dc.identifier.volume80en_US
dc.identifier.wosWOS:000311950000034en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofUrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPharmacotherapyen_US
dc.subjectSildenafilen_US
dc.subjectMenen_US
dc.titleAutonomic Nervous System Dysfunction in Lifelong Premature Ejaculation: Analysis of Heart Rate Variabilityen_US
dc.typeArticleen_US

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