Prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease

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dc.authoridSangun, Ozlem/0000-0002-9079-4574
dc.contributor.authorBalcı, Ali
dc.contributor.authorKarazincir, Sinem
dc.contributor.authorSanguen, Oezlem
dc.contributor.authorGali, Edip
dc.contributor.authorDaplan, Turgay
dc.contributor.authorCingiz, Cihangir
dc.contributor.authorEgilmez, Ertugrul
dc.date.accessioned2024-09-18T20:57:01Z
dc.date.available2024-09-18T20:57:01Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPURPOSE The aim of this study was to evaluate the type and prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease. MATERIALS AND METHODS A total of 102 patients with sickle cell disease at the Center of Hemoglobinopathy of the Antakya State Hospital were screened for intra-abdominal abnormalities by abdominal ultrasonography (US). Eighty-four patients were homozygous or sickle-cell disease (S/S), and 18 patients were compound heterozygotes for sickle cell-beta thalassemia (S/beta(thal)). At the time of examination, 15.7% (16/102) of patients had undergone gone splenectomy, and 18.6% (19/102) of patients had undergone cholecystectomy. RESULTS The most frequent US findings (expressed as percentages of all patients) were hepatomegaly (71.6%), renal enlargement (30.4%), autosplenectomy (33.3%), cholelithiasis (30.4%) and splenomegaly (17.4%). A bright liver was identified in 6 patients (5.9%), an echogenic pancreas in 4 patients (3.9%), and pancreatic punctate echogenic foci were identified in 5 patients (4.9%). Medullary or diffusely increased renal echogenicity was observed in 16 patients (15.7%). Sonographic findings typical of renal papillary necrosis were observed in one patient with S/S. Periportal lymphadenopathy was detected in 10 (11.9%) of 84 patients of the S/S group, and 2 (11.1%) of 18 patients of S/beta(thal) group. CONCLUSION Abdominal ultrasonographic imaging of patients with sickle cell disease revealed a high prevalence of abdominal abnormalities, especially in solid organs.en_US
dc.identifier.endpage137en_US
dc.identifier.issn1305-3825
dc.identifier.issue3en_US
dc.identifier.pmid18814134en_US
dc.identifier.scopus2-s2.0-55149091549en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage133en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12245
dc.identifier.volume14en_US
dc.identifier.wosWOS:000258776600006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Radiologyen_US
dc.relation.ispartofDiagnostic and Interventional Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectsickle cell diseaseen_US
dc.subjectultrasonographyen_US
dc.subjectabdomenen_US
dc.subjectliveren_US
dc.subjectkidneyen_US
dc.titlePrevalence of abdominal ultrasonographic abnormalities in patients with sickle cell diseaseen_US
dc.typeArticleen_US

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