Comparison of systemic immune-inflammation index levels in patients with isolated coronary artery ectasia versus patients with obstructive coronary artery disease and normal coronary angiogram

Basit Öğe Kaydı
dc.authoridAkbulut, Muge/0000-0002-9190-0009
dc.authoridYamanturk, Yakup Yunus/0000-0003-2636-4710
dc.contributor.authorEsenboga, Kerim
dc.contributor.authorKurtul, Alparslan
dc.contributor.authorYamanturk, Yakup Yunus
dc.contributor.authorAkbulut, Irem Muge
dc.contributor.authorTutar, Durmus Eralp
dc.date.accessioned2024-09-18T20:13:22Z
dc.date.available2024-09-18T20:13:22Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractCoronary artery ectasia (CAE) is associated with increased risk of mortality, equivalent to that of patients with obstructive coronary artery disease (CAD). Considering the role of inflammation in the pathogenesis of CAE, we aimed to investigate whether there is an association between systemic immune-inflammation index (SII) and isolated CAE. The study population included 510 patients of which 170 patients with isolated CAE, 170 patients with obstructive CAD and 170 patients with normal coronary angiograms (NCA). The severity of CAE was determined according to the Markis classification. Patients with isolated CAE had significantly higher SII values compared to those with obstructive CAD and NCA [median 550 IQR (404-821), median 526 IQR (383-661), and median 433 IQR (330-555), respectively, p < .001]. In multivariate analysis, SII (OR 1.032, 95% CI 1.020-1.044, p = .003), male gender (OR 2.083, p = .008), eGFR (OR 0.979, p = .016), and CRP (OR 1.105, p = .005) were independent factors of isolated CAE. Moreover, in the Spearman correlation analysis, there was a moderate but significant positive correlation between SII and CRP (r = 0.379, p < .001). In conclusion, higher SII levels were independently associated with the presence of isolated CAE. This result suggests that a more severe inflammatory process may play a role in the development of this variant of CAD.en_US
dc.identifier.doi10.1080/00365513.2022.2034034
dc.identifier.endpage137en_US
dc.identifier.issn0036-5513
dc.identifier.issn1502-7686
dc.identifier.issue2en_US
dc.identifier.pmid35143364en_US
dc.identifier.scopus2-s2.0-85125145188en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage132en_US
dc.identifier.urihttps://doi.org/10.1080/00365513.2022.2034034
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9131
dc.identifier.volume82en_US
dc.identifier.wosWOS:000753790100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofScandinavian Journal of Clinical & Laboratory Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronary artery ectasiaen_US
dc.subjectsystemic immune-inflammation indexen_US
dc.subjectinflammationen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectMarkis classificationen_US
dc.titleComparison of systemic immune-inflammation index levels in patients with isolated coronary artery ectasia versus patients with obstructive coronary artery disease and normal coronary angiogramen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu