Evaluation of the aquaporin molecules characterization in the sperm cells of men from different aged

Basit Öğe Kaydı
dc.contributor.authorGevrek, Fikret
dc.contributor.authorGencel, Osman Serden
dc.contributor.authorGorgun, Selim
dc.contributor.authorKara, Mikail
dc.contributor.authorKatar, Muzaffer
dc.date.accessioned2024-09-18T20:02:36Z
dc.date.available2024-09-18T20:02:36Z
dc.date.issued2024
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground/aim: Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups. Material and methods: This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18-25 years (n = 20); group 2, age 26-35 years (n = 20); and group 3, age >= 35 years (n = 20). Sperm ejaculates obtained from each participant were used for spermiogram tests, Kruger strict morphology analysis, and immunohistochemistry. Results: We observed no statistically significant differences in terms of macroscopic and microscopic sperm testing. The immunostaining score of aquaporin-3 was the lowest in group 1 and increased in group 3 and group 2, respectively (p < 0.05). Aquaporin-8 immunostaining only increased in group 2 (p < 0.05). Aquaporin-7 immunostaining scores were not different between the groups (p > 0.05). When the immunostaining scores of aquaporin molecules were compared with each other, aquaporin-7 was significantly increased compared with the others (p < 0.05). Conclusion: According to the results, it can be stated that aquaporin-3 and aquaporin-8 molecules were more expressed at age 26 to 35 years, and aquaporin-7 was densely expressed from age 18 to 25 years. If the characterization of these molecules is adversely affected, male infertility may eventually emerge. We recommend further advanced -level studies on this subject.en_US
dc.identifier.doi10.55730/1300-0144.5781
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.pmid38812647en_US
dc.identifier.scopus2-s2.0-85185672360en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.55730/1300-0144.5781
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7894
dc.identifier.volume54en_US
dc.identifier.wosWOS:001171489500030en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAquaporin moleculesen_US
dc.subjectfertilityen_US
dc.subjectimmunostainingen_US
dc.subjectinfertilityen_US
dc.subjectspermen_US
dc.titleEvaluation of the aquaporin molecules characterization in the sperm cells of men from different ageden_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
7894.pdf
Boyut:
821.72 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu