Effect of 1-deamino 8-D-arginine vasopressin spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis
Yükleniyor...
Tarih
2006
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: To determine any possible adverse effect of 1-deamino 8-D-arginine vasopressin (DDAVP) spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis. Methods: Twenty-two children aged 6-16 enrolled in the study. Epithelial surface cells samples were taken from the nasal mucosa and mucociliary clearance time was calculated before and 1 and 6 months after administration of DDAVP spray. Results: No qualitative changes in the epithelial surface cells and mucociliary clearance time were observed at 1 and 6 months after therapy. Conclusion: Based on the findings of the present study, DDAVP spray can be used for 6 months in children without apparent risk of damage to the epithelial surface cells and mucociliary clearance time. (C) 2006 Elsevier Ireland Ltd. Atl. rights reserved.
Açıklama
Anahtar Kelimeler
nocturnal enuresis, DDAVP spray, vasopressin, nasal mucosa, nocturnal enuresis
Kaynak
International Journal of Pediatric Otorhinolaryngology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
70
Sayı
11