In vitro and in vivo antifungal activity of synthetic pure isothiocyanates against Sclerotinia sclerotiorum

dc.authoridSOYLU, Soner/0000-0003-1002-8958
dc.authoridSoylu, Emine Mine/0000-0001-5961-0848
dc.contributor.authorKurt, Sener
dc.contributor.authorGunes, Ufuk
dc.contributor.authorSoylu, Emine M.
dc.date.accessioned2024-09-18T20:56:53Z
dc.date.available2024-09-18T20:56:53Z
dc.date.issued2011
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBACKGROUND: Isothiocyanates (ITCs) released by the enzymatic hydrolysis of glucosinolates in the Brassicaceae are potentially useful for controlling fungal pathogens. In vitro activity of pure ITCs against Sclerotinia sclerotiorum (Lib.) de Bary was studied by adding them to glass filters in petri dishes and dissolving them in the growing media. RESULTS: Methyl, allyl and benzyl ITCs were the most fungitoxic of the compounds in bioassays with S. sclerotiorum isolate Ss31. In the volatile phase, mycelial growth was completely inhibited by these three compounds. Aromatic ITCs were less toxic in the petri dishes but were more toxic than aliphatic ITCs when dissolved in the agar. Benzyl ITC exhibited the highest inhibitory effect on sclerotial germination, with an EC50 value of 75.1 mu mol L-1. Butyl and benzyl ITCs reduced apothecial production of S. sclerotiorum by 92.5% at the highest concentration. In in vivo assay, only allyl and 2-phenylethyl ITCs reduced disease incidence (by 76.7 and 70% respectively) at low concentrations. CONCLUSION: Sclerotinia sclerotiorum in the soil might be suppressed by the higher concentrations of allyl and benzyl ITCs released from decomposition of Brassica juncea, B. carinata, B. nigra and Sinapis spp. (C) 2011 Society of Chemical Industryen_US
dc.description.sponsorshipScientific and Technical Research Council of Turkey (TUBITAK), Ankara [1080304]en_US
dc.description.sponsorshipThis research was supported by project number 1080304 from the Scientific and Technical Research Council of Turkey (TUBITAK), Ankara. The authors thank Drs Fatih Evrendilek and Mehmet Arslan for their critical readings of the manuscript.en_US
dc.identifier.doi10.1002/ps.2126
dc.identifier.endpage875en_US
dc.identifier.issn1526-498X
dc.identifier.issn1526-4998
dc.identifier.issue7en_US
dc.identifier.pmid21370393en_US
dc.identifier.scopus2-s2.0-79958843259en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage869en_US
dc.identifier.urihttps://doi.org/10.1002/ps.2126
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12151
dc.identifier.volume67en_US
dc.identifier.wosWOS:000292411800017en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJohn Wiley & Sons Ltden_US
dc.relation.ispartofPest Management Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSclerotinia sclerotiorumen_US
dc.subjectisothiocyanatesen_US
dc.subjectantifungal activityen_US
dc.titleIn vitro and in vivo antifungal activity of synthetic pure isothiocyanates against Sclerotinia sclerotiorumen_US
dc.typeArticleen_US

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