Effectiveness of Booster Measles-Mumps-Rubella Vaccination in Lower COVID-19 Infection Rates: A Retrospective Cohort Study in Turkish Adults

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dc.authoridyengil, erhan/0000-0002-4198-4873
dc.contributor.authorYengil, Erhan
dc.contributor.authorOnlen, Yusuf
dc.contributor.authorOzer, Cahit
dc.contributor.authorHambolat, Mustafa
dc.contributor.authorOzdogan, Mehmet
dc.date.accessioned2024-09-18T20:13:27Z
dc.date.available2024-09-18T20:13:27Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to investigate the effectiveness of booster vaccination of adults with measles-mumps-rubella in the COVID-19 infection rates. Methods: In order to investigate this hypothesis, we tested COVID-19 positivity rate through PCR assay on the participants (n=245; male), who had to share the same student accommodation together with the same dining hall to provide governmental service. Participants were divided into two groups based on their booster vaccination status with measles-mumps-rubella: the non-vaccinated group (n=207) and the vaccinated group (n=38). The rate of COVID-19 seropositivity, age, body mass index (BMI), active smoking and presence of comorbidity were also measured and recorded. Results: All of the participants were healthy, and age distribution, comorbidity rates, active smoking status and BMI did not vary significantly among the two groups (p=0.305, p=0.594, p=0.280, and p=0.922, respectively). About 36.7% (n=90) of the participants were found to be COVID-19 positive by PCR among which the non-vaccinated cases had higher rates of COVID-19 seropositivity than the vaccinated cases (40.6% vs 15.8%) (OR=3.6, 95%CI: 1.5-9.0, p=0.004). Conclusion: Based on these results, we cautiously predict that immunity produced by MMR vaccination boosters may provide some degree of protection against COVID-19 in the adult population.en_US
dc.identifier.doi10.2147/IJGM.S309022
dc.identifier.endpage1762en_US
dc.identifier.issn1178-7074
dc.identifier.pmid33994804en_US
dc.identifier.scopus2-s2.0-85106303269en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1757en_US
dc.identifier.urihttps://doi.org/10.2147/IJGM.S309022
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9195
dc.identifier.volume14en_US
dc.identifier.wosWOS:000648174300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDove Medical Press Ltden_US
dc.relation.ispartofInternational Journal of General Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectlive attenuated vaccinesen_US
dc.subjectbooster vaccinationen_US
dc.subjectMMRen_US
dc.titleEffectiveness of Booster Measles-Mumps-Rubella Vaccination in Lower COVID-19 Infection Rates: A Retrospective Cohort Study in Turkish Adultsen_US
dc.typeArticleen_US

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