Insulin Like Growth Factor (IGF)
[ N/A ]
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Insulin Like Growth Hormone (IGF) is a peptide family, depends on and suplying most of the anabolic and mitogenic effects of growth hormon (GH). Beside its GH dependance of serum consantration, showing its effects in tissues other than skeletal ones, increasing the binding of sulphate to the cartilage, stimulating the DNA synthesis and cell proliferation it has also some other duties. IGF-1 is a sample peptide of 70 aminoacids also celled SM-C. IGF-2 is an acidic peptide composed of 67 aminoacids. In both peptides 45 of the 73 aminoacid position are same and almost % 50 aminoacid of them also same with insulin. Both IGF consists of A and D chains binding with disulphide bindings like insulin. We present this review so as to evaluate the findings of the studies made in recent years about Insulin Like Growth Factor.
Açıklama
Anahtar Kelimeler
growth hormone, somatomedin, biosynthesis, cartilage, cell proliferation, DNA synthesis, hormone action, mitogenesis, review
Kaynak
SENDROM
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
16
Sayı
6
