Fatty acid, tocopherol, mineral composition, total phenolic, flavonoid, thymoquinone content, and antioxidant activity of Nigella Sativa L.

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dc.authorscopusid56450878400
dc.authorscopusid56451207800
dc.authorscopusid7801321287
dc.authorscopusid6603473741
dc.contributor.authorUras, S. Selma
dc.contributor.authorSilahtaro?lu, Sibel
dc.contributor.authorIlçim, Ahmet
dc.contributor.authorKökdil, Gamze
dc.date.accessioned2024-09-19T15:43:34Z
dc.date.available2024-09-19T15:43:34Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe fatty acid and tocopherol composition of fixed oil from seeds of Nigella sativa L. has been investigated by GC-MS and HPLC, respectively. Linoleic and oleic acids were the main fatty acids. The major tocopherols were ?- and ?-tocopherols. The total phenolic and flavonoid content and primary antioxidant activity of aqueous methanolic extracts of different parts of N.sativa were measured. Total phenolic content was assessed by Folin-Ciocalteu method and the content of flavonoids was measured spectrophotometrically by using the AlCl3 assay. Primary antioxidant activity in terms of free radical scavenging activity of the extracts was evaluated by DPPH assay. The present study showed that the seed extract contained significantly higher amount of total phenolic compounds than aerial part extract. The total flavonoid content ranged between 106.10±0.10 and 118.06±0.02 mg rutin equivalent per g extracts. The thymoquinone content in seeds were quantified by RP-HPLC analysis and the concentration ofthymoquinone was 268.3 ?g/mL. In DPPH radical scavenging assay, inhibition % of the extracts was found to be 95.09-90.71. The seeds also were analyzed by ICP-MS to determine mineral content. P, K, Ca and Mg were predominant elements among seventeen minerals in the seeds.en_US
dc.identifier.endpage186en_US
dc.identifier.issn2564-6524
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84918792867en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage173en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14417
dc.identifier.volume39en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherUniversity of Ankaraen_US
dc.relation.ispartofAnkara Universitesi Eczacilik Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant activityen_US
dc.subjectFatty aciden_US
dc.subjectMineralen_US
dc.subjectNigella sativa L.en_US
dc.subjectPhenolicsen_US
dc.subjectTocopherolsen_US
dc.titleFatty acid, tocopherol, mineral composition, total phenolic, flavonoid, thymoquinone content, and antioxidant activity of Nigella Sativa L.en_US
dc.title.alternativeNigella Sativa L.'Nin ya? asidi, tokoferol, mineral bileşimi, total fenolik, flavonoit, timokinon miktari ve antioxidan activitesien_US
dc.typeArticleen_US

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