Evaluation of the In vitro Bioactivities of Mahaleb Cherry (Prunus mahaleb L.)

Basit Öğe Kaydı
dc.authoridkoca, ufuk/0000-0002-5216-7588
dc.authoridKaya, Durmus Alpaslan/0000-0003-3544-9214
dc.contributor.authorOzcelik, Berrin
dc.contributor.authorKoca, Ufuk
dc.contributor.authorKaya, Durmus Alpaslan
dc.contributor.authorSekeroglu, Nazim
dc.date.accessioned2024-09-18T19:54:27Z
dc.date.available2024-09-18T19:54:27Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractThe mahaleb cherry (Prunus mahaleb L.), a wild member of the Rosaceae family, is an important rootstock for cherry and sour cherry cultivars. Besides horticultural importance, all parts of the plant, specifically the seeds and fruits have been used to give flavor and taste to a variety of its cousins in Mediterranean countries for centuries. The seeds of mahaleb are an important industrial crop in Turkey; moreover, folkloric usage of the other parts of the plant has also been recorded. In the present study, methanol and n-hexane extracts from different parts of the mahaleb cherry including the flower, leaves, branches, fruits, fruit stalk, seeds and seed coat were screened for in-vitro antibacterial, antifungal and radical scavenging activity using the DPPH method. Standard strains of E. coli, P. aeruginosa, P. mirabilis, K. pneumoniae, A. baumannii, S. aureus, E. faecalis and B. subtilis with their pathogens from clinical isolates as well as fungi (C. albicans, C. parapsilosis, C. tropicalis and C. krusei) were used to determine the antimicrobial activity. All extracts showed antibacterial activity against gram-positive standard bacteria with concentrations between 16-64 mu g mL(-1) and against gram-negative bacteria (8-64 mu g mL(-1)). Additionally, the extracts demonstrated antifungal activity at concentrations between 16-64 mu g mL(-1). The minimal inhibition concentration (MIC) value of the extracts against all gram-positive and gram-negative isolated strains was 250 mu g mL(-1) excluding B. subtilis (MIC: 64 mu g mL(-1)). As for antifungal activity, all methanol and n-hexane extracts were found to inhibit C. krusei, with a MIC value of 64 mu g mL(-1), which is better than the control fluconazole (64 mu g mL(-1)). Methanol extracts of mahaleb had better antioxidant activity than all n-hexane extracts. The methanol extract of fruit samples (Mfr) displayed better antioxidant activity (86.25 +/- 0.12) than the reference BHA solution (83.633 +/- 0.22) at all concentrations except for 100 mu g mL(-1). Antioxidant levels of methanol extracts from mahaleb seed kernel (Msk), leaves (Ml), branches (Mb) and fruit stalks followed the Mfr samples. The strong antimicrobial, antifungal and antioxidant activities of the mahaleb plant indicate that in the future, it may be important for clinical nutrition and the food and pharmaceutical industries.en_US
dc.identifier.endpage7872en_US
dc.identifier.issn1224-5984
dc.identifier.issue6en_US
dc.identifier.startpage7863en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7748
dc.identifier.volume17en_US
dc.identifier.wosWOS:000312797400017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherArs Docendien_US
dc.relation.ispartofRomanian Biotechnological Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterialen_US
dc.subjectAntifungalen_US
dc.subjectAntioxidanten_US
dc.subjectMahaleb cherryen_US
dc.subjectPrunus mahaleb L.en_US
dc.subjectRosaceaeen_US
dc.titleEvaluation of the In vitro Bioactivities of Mahaleb Cherry (Prunus mahaleb L.)en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
Ä°sim:
7748.pdf
Boyut:
257.45 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
Ä°ndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu