Effects of a Single Application of Adcon Gel on Peritendinous Adhesion: An Experimental Study in Rabbits

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dc.contributor.authorOzden, Raif
dc.contributor.authorUruc, Vedat
dc.contributor.authorDuman, Ibrahim Gokhan
dc.contributor.authorDogramaci, Yunus
dc.contributor.authorKalacı, Aydıner
dc.contributor.authorKomurcu, Erkam
dc.contributor.authorOzsoy, Sule Yurdagul
dc.date.accessioned2024-09-18T19:50:22Z
dc.date.available2024-09-18T19:50:22Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPeritendinous adhesions are serious complications after surgical repair of tendons and can lead to poor functional outcome. In the present study, the tensile strength of repaired tendons was measured biomechanically in two groups using a rabbit Achilles tendon model, and the effects of Adcon gel on peritendinous adhesions and tendon healing were examined by means of histological and mechanical analyses. In the treatment group, the Achilles tendon was transected, followed by a primary repair using a modified Kessler technique, and Adcon gel was injected between the tendon and skin of the right leg. The same operation was done for the control group, and 1 mL of normal saline solution was applied locally in a similar fashion. The experimental protocols were approved by the local animal ethics committee. Microscopic evidence of the formation of adhesions and of inflammation was less in the treatment group than in the control group. There was no significant difference in the tensile load necessary to rupture the repaired tendons between the two groups. Adcon gel reduced the peritendinous adhesions histologically without impairing tendon healing, as determined with mechanical analyses. The use of Adcon gel may provide a simple means of preventing of postoperative peritendinous adhesions, thereby offering a beneficial effect on tendon repair.en_US
dc.identifier.doi10.2485/jhtb.23.199
dc.identifier.endpage203en_US
dc.identifier.issn1341-7649
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84898485902en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage199en_US
dc.identifier.urihttps://doi.org/10.2485/jhtb.23.199
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7395
dc.identifier.volume23en_US
dc.identifier.wosWOS:000334561600008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherJournal Hard Tissue Biologyen_US
dc.relation.ispartofJournal of Hard Tissue Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdcon gelen_US
dc.subjectTendon injuryen_US
dc.subjectPeritendinous adhesionen_US
dc.titleEffects of a Single Application of Adcon Gel on Peritendinous Adhesion: An Experimental Study in Rabbitsen_US
dc.typeArticleen_US

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