Anxiety, depression and quality of life in patients with beta thalassemia major and their caregivers

dc.authoridkurhan, faruk/0000-0003-3718-0458
dc.contributor.authorYengil, Erhan
dc.contributor.authorAcipayam, Can
dc.contributor.authorKokacya, Mehmet Hanifi
dc.contributor.authorKurhan, Faruk
dc.contributor.authorOktay, Gonul
dc.contributor.authorOzer, Cahit
dc.date.accessioned2024-09-18T20:04:24Z
dc.date.available2024-09-18T20:04:24Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractMental health and health related quality of life is commonly affected in patients with chronic problems and their caregivers. In the present study, it was aimed to assess depression and anxiety in patients with beta thalassemia major (BTM) and in their caregivers; and to evaluate effects of these disorders on quality of life. The study was carried out in a district Hereditary Hemoglobinopathy Center and included 88 patients with BTM and 63 of their caregivers. All subjects were assessed using Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Short Form-36 (SF-36) by a trained psychiatry resident via face-to-face interview. The BDI scores were 17 or above in 20.5% of the patients with BTM and 28.6% of their caregivers (P = 0.248). Of the patients with BTM, there were mild anxiety symptoms in 19.3%, while moderate and severe anxiety symptoms in 14.8% and 4.5%, respectively. Anxiety levels were similar between the patients with BTM and their caregivers (P = 0.878). It was found that BDI and BAI scores were negatively correlated to scores of physical health and mental health components of SF-36 in patients with BTM and their caregivers. In linear regression analysis, it was seen that depression affected physical and mental health of the patients with BTM and their caregivers regardless from anxiety. BTM leads an increase in the frequency of depression and anxiety in both patients and their caregivers, and affects negatively physical and mental components of quality of life.en_US
dc.identifier.endpage2172en_US
dc.identifier.issn1940-5901
dc.identifier.issue8en_US
dc.identifier.pmid25232402en_US
dc.identifier.scopus2-s2.0-84907214368en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage2165en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8144
dc.identifier.volume7en_US
dc.identifier.wosWOS:000341257500031en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBeta-thalassemiaen_US
dc.subjectquality of lifeen_US
dc.subjectanxietyen_US
dc.subjectdepressionen_US
dc.subjectcaregiversen_US
dc.titleAnxiety, depression and quality of life in patients with beta thalassemia major and their caregiversen_US
dc.typeArticleen_US

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