Can preoperative inflammatory markers predict the success of varicocelectomy?

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dc.authoridtoksoz, serdar/0000-0002-2649-1157
dc.authoridsenel, samet/0000-0003-2280-4192
dc.authoridKizilkan, Yalcin/0000-0002-4729-0100
dc.authoridDURAN, Mesut Berkan/0000-0002-8597-2081
dc.authoridYIKILMAZ, Taha Numan/0000-0001-8410-2474
dc.contributor.authorDuran, Mesut Berkan
dc.contributor.authorKizilkan, Yalcin
dc.contributor.authorSenel, Samet
dc.contributor.authorYikilmaz, Taha Numan
dc.contributor.authorToksoz, Serdar
dc.date.accessioned2024-09-18T20:28:07Z
dc.date.available2024-09-18T20:28:07Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the effect of inflammation on the success of varicocelectomy by using some inflammatory markers. Adult male patients aged >= 18 years who were evaluated for infertility, had abnormal parameters in at least two preoperative semen analyses and underwent subinguinal microscopic varicocelectomy were retrospectively evaluated. The patients were divided into two groups; those showing improvement in semen parameters were determined as Group A and those without improvement as Group B and compared with each other. A total of 102 patients were included in this study. Group A contained 32 (31.4%) patients while Group B had 70 (68.6%) patients. Monocyte/lymphocyte ratio (MLR) and neutrophil/lymphocyte ratio (NLR) were found to be statistically significantly higher in Group B (p = 0.014 and p = 0.028 respectively). Although preoperative sperm concentration and total motile sperm count were higher in Group B, postoperative all semen parameters were significantly higher in Group A. The cutoff points that were determined using the Youden test were <2.02 for NLR (AUC = 0.636, CI = 0.519-0.754; p = 0.028) and <0.22 for MLR (AUC = 0.652, CI = 0.531-0.773; p = 0.014). Pre-varicocelectomy low NLR and MLR values were found to be significant parameters in predicting the success of the surgery.en_US
dc.identifier.doi10.1111/and.14514
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.pmid35753707en_US
dc.identifier.urihttps://doi.org/10.1111/and.14514
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10745
dc.identifier.wosWOS:000815650100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectinfertilityen_US
dc.subjectinflammationen_US
dc.subjectinflammatory markeren_US
dc.subjectvaricoceleen_US
dc.subjectvaricocelectomyen_US
dc.titleCan preoperative inflammatory markers predict the success of varicocelectomy?en_US
dc.typeArticleen_US

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