Use of selamectin for the treatment of psoroptic and sarcoptic mite infestation in rabbits

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dc.contributor.authorKurtdede, Arif
dc.contributor.authorKaraer, Zafer
dc.contributor.authorAcar, Abuzer
dc.contributor.authorGuzel, Murat
dc.contributor.authorCingi, C. Cagri
dc.contributor.authorUral, Kerem
dc.contributor.authorIca, Anil
dc.date.accessioned2024-09-18T21:05:16Z
dc.date.available2024-09-18T21:05:16Z
dc.date.issued2007
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractSelamectin, a novel avermectin compound, was evaluated for its efficacy against naturally occurring infestations of Psoroptes cuniculi and Sarcoptes scabiei. A total of 42 New Zealand rabbits with psoroptic mange and 37 Angora rabbits with sarcoptic mange were used in the present study. On day 0, infested rabbits were treated topically with either selamectin at minimum dose of 6 mg kg(-1) (6-18 mg kg(-1) for New Zealand rabbits, n = 31 and 10-12 mg kg(-1) for Angora rabbits, n = 23) or vehicle only (control groups, n = 11 for New Zealand rabbits, n = 14 for Angora rabbits). The efficacy of selamectin was assessed both clinically and parasitologically by the presence or absence of viable mites. Rabbits were scraped for sarcoptic mites on days 7, 14, 28, 42 and 56 and had otoscopeic and/or microscopic examination for the detection of Psoroptes mites on days 7, 14, 42 and 56. Fisher's exact test was used to assess differences between the vehicle and selamectin treatment in the number of rabbits without mites (cure rates) on each assessment date. It was found that significantly fewer selamectin-treated rabbits had mites detected on skin scrapings (for S. scabiei) or otoscopeic and/or microscopic examination (for P. cuniculi) (P < 0.01) than the vehicle group. Results of the present study suggest that selamectin is effective against naturally infestations of P. cuniculi and S. scabiei in rabbits.en_US
dc.identifier.doi10.1111/j.1365-3164.2007.00563.x
dc.identifier.endpage22en_US
dc.identifier.issn0959-4493
dc.identifier.issn1365-3164
dc.identifier.issue1en_US
dc.identifier.pmid17222235en_US
dc.identifier.scopus2-s2.0-33845998584en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage18en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-3164.2007.00563.x
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13483
dc.identifier.volume18en_US
dc.identifier.wosWOS:000243309200004en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofVeterinary Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOtodectes-Cynotisen_US
dc.subjectEfficacyen_US
dc.subjectDogsen_US
dc.subjectIvermectinen_US
dc.subjectCuniculien_US
dc.subjectScabieien_US
dc.subjectSafetyen_US
dc.titleUse of selamectin for the treatment of psoroptic and sarcoptic mite infestation in rabbitsen_US
dc.typeArticleen_US

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