Sensitivity of [18F]FDG PET/CT and classification of the primary tumor site in patients with carcinoma of unknown primary

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dc.contributor.authorAtilgan, Hasan Ikbal
dc.contributor.authorYalcin, Hulya
dc.date.accessioned2024-09-18T20:54:24Z
dc.date.available2024-09-18T20:54:24Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: The aim of this study is to find the sensitivity of the [F-18]FDG PET/CT and the classification of the primary sites of carcinoma of unknown primary (CUP) as a single-center experience. Material and methods: Sixty-eight patients with a mean age of 62.43 +/- 12.78 years were included in this study retrospectively. Sixty-five patients had biopsy or surgery after PET/CT, which revealed pathological diagnoses of malign primary tumors, while primary tumor site could not be detected in three patients with histopathological examination. We evaluated the primary site of CUP with [F-18]FDG PET/CT. Results: Primary sites of three patients were not determined by histopathological examination. Malign lesions indicating the primary site of tumor were identified in 52 of 68 patients with PET/CT correctly. The primary tumor was lung cancer in 14 patients, cholangiocellular cancer in 9 patients, lymphoma in 9 patients, pancreas cancer in 6 patients, gastric cancer in 4 patients, ovary cancer in 4 patients, colon cancer in 4 patients, breast cancer in 3 patients, hepatocellular cancer in 2 patients, rectal cancer in 2 patients, sarcoma in 2 patients, esophagus, renal cell cancer, squamous cell cancer, endometrium cancer, malign mela-noma, and multiple myeloma in 1 patient with histopathological examination. PET/CT was false positive in one patient. There were 13 patients in whom primary tumor could not be localized by PET/CT, but was diagnosed by histopathological evaluation. Conclusions: PET/CT should be the first-line diagnostic tool for CUP, other diagnostic imaging tools should be applied after a negative whole-body PET/CT.en_US
dc.identifier.doi10.5603/NMR.a2022.0002
dc.identifier.endpage5en_US
dc.identifier.issn1506-9680
dc.identifier.issn1644-4345
dc.identifier.issue1en_US
dc.identifier.pmid35137930en_US
dc.identifier.scopus2-s2.0-85124324400en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.5603/NMR.a2022.0002
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11788
dc.identifier.volume25en_US
dc.identifier.wosWOS:000754068300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofNuclear Medicine Reviewen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpositron emission tomography-computed tomographyen_US
dc.subjectunknown primary tumorsen_US
dc.subjectF-18-fluorodeoxyglucoseen_US
dc.titleSensitivity of [18F]FDG PET/CT and classification of the primary tumor site in patients with carcinoma of unknown primaryen_US
dc.typeArticleen_US

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