Molecular Characterization of Methicillin-and Multidrug-Resistant Staphylococcus pseudintermedius Strain Isolated from a Case of Feline Otitis Externa
[ N/A ]
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Israel Veterinary Medical Association
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an emerging zoonotic pathogen in veterinary medicine. Whole-genome sequencing (WGS) is highly preferred today as a valid method for molecular typing of bacterial pathogens due to its high discriminatory power and characterization efficiency. This study describes the WGS–based characterization of an MRSP strain named HMKU-VET-MRSP-2020 from a case of cat otitis externa in Türkiye. The strain was classified as MLST sequence type 71 and SCCmec type IIIA. WGS analysis indicated the presence of several antimicrobial resistance genes and mutations consistent with the resistance phenotype. Phylogenetic analysis showed that the strain was clusterized with the isolates from dog clinical cases previously reported from different countries of Europe and one human isolate from the USA. The study is the first report on the isolation and molecular characterization of MRSP from a cat in Türkiye and provides insights into the zoonotic potential of this microorganism. © 2023, Israel Veterinary Medical Association. All rights reserved.
Açıklama
Anahtar Kelimeler
Cat, Methicillin Resistance, Staphylococcus pseudintermedius, Whole-Genome Sequencing
Kaynak
Israel Journal of Veterinary Medicine
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
78
Sayı
1
