Assessment of Neutrophil/Lymphocyte Ratio in Patients with Age-related Macular Degeneration

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dc.contributor.authorIlhan, Nilufer
dc.contributor.authorDaglioglu, Mutlu Cihan
dc.contributor.authorIlhan, Ozgur
dc.contributor.authorCoskun, Mesut
dc.contributor.authorTuzcu, Esra Ayhan
dc.contributor.authorKahraman, Hilal
dc.contributor.authorKeskin, Ugurcan
dc.date.accessioned2024-09-18T19:52:30Z
dc.date.available2024-09-18T19:52:30Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: To investigate the neutrophil/lymphocyte ratio (NLR) as an indicator of inflammation in patients with age-related macular degeneration (AMD). Methods: Patients were evaluated by a review of records. The study included 81 patients with dry AMD (group 1), 84 patients with wet AMD (group 2), and 80 healthy age-and sex-matched controls (group 3). The NLR of the patients was obtained from the hospital laboratory archive and was measured by dividing the neutrophil count by the lymphocyte count. Results: A significant difference was found in NLR values between groups 1 and 2 (p = 0.017), groups 2 and 3 (p<0.001), and groups 1 and 3 (p<0.001). In correlation analyses, NLR was correlated positively with age (r = 0.22, p<0.001) and disease severity (r = 0.40, p<0.001). Conclusions: Patients with AMD have higher NLR compared with controls, and NLR correlates with disease severity. NLR may be used as a biomarker of inflammation in AMD.en_US
dc.identifier.doi10.3109/09273948.2014.921715
dc.identifier.endpage290en_US
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue4en_US
dc.identifier.pmid24987927en_US
dc.identifier.scopus2-s2.0-84939429475en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage287en_US
dc.identifier.urihttps://doi.org/10.3109/09273948.2014.921715
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7463
dc.identifier.volume23en_US
dc.identifier.wosWOS:000361333100005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofOcular Immunology and Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAge-related macular degenerationen_US
dc.subjectblindnessen_US
dc.subjectinflammationen_US
dc.subjectneutrophil/lymphocyte ratioen_US
dc.subjectretinal drusenen_US
dc.titleAssessment of Neutrophil/Lymphocyte Ratio in Patients with Age-related Macular Degenerationen_US
dc.typeArticleen_US

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