Evaluation of hs-CRP and visseral adiposity index in patients with policystic ovary syndrome by clinical and laboratory findings

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dc.contributor.authorUn, B.
dc.contributor.authorDolapcioglu, K. S.
dc.contributor.authorOkyay, A. Guler
dc.contributor.authorSahin, H.
dc.contributor.authorBeyazit, A.
dc.date.accessioned2024-09-18T20:54:07Z
dc.date.available2024-09-18T20:54:07Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: In this study, we aimed to evaluate two cardiovascular risk markers, hs-CRP and visseral adiposity index, in patients with policystic ovary syndrome in association with clinical and laboratory findings. Material and method: Study group included 75 patients who were diagnosed as PCOS according to the criteria of AE-PCOS 2006 and control group included 75 non-PCOS patients who were subsequently admitted to outpatient clinic for smear control, with urinary or vaginal symptoms. Physical and sonographic examinations were made to all subjects. Mean arterial pressure, waist/hip ratio and body mass index were calculated. Fasting blood glucose and insulin, HbA1c, lipids, high sensitivity C-reactive protein (hs-CRP), estradiol, follicle stimulating hormon, luteinising hormone, timid stimulating hormone, prolaktin, total testosteron and sex hormone binding globulin were tested in venous blood samples collected from cases following overnight fast in follicular phase of spontaneous or induced menstruation. Visceral adiposity index was also calculated. Findings: No statistically significant difference was found between PCOS group and control group concerning hs-CRP and VAI (p > 0.05). When patients in PCOS group were further grouped as obese and non-obese, hs-CRP and VAI values in obese group were significantly higher than those in non-obese. group (p < 0.001). However, when control group were further grouped as obese and non-obese, there was no significant difference in terms of hs-CRP between groups (p > 0.05), VAI values were significantly higher in obese control group (p < 0.05). Conclusion: According to the results of our study, hs-CRP stands for a better and more specific marker than VAI to determine metabolic components and predictive risks for cardiovascular diseases in patients with PCOS. Further studies with larger populations are needed in order to determine cardiovascular risks particularly in young PCOS patients. (C) 2016 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejogrb.2016.06.022
dc.identifier.endpage20en_US
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.pmid27479317en_US
dc.identifier.scopus2-s2.0-84979699619en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage16en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2016.06.022
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11597
dc.identifier.volume204en_US
dc.identifier.wosWOS:000385321900004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofEuropean Journal of Obstetrics & Gynecology and Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPCOSen_US
dc.subjecths-CRPen_US
dc.subjectVisceral adiposity index (VAI)en_US
dc.subjectCardiovascular disease markeren_US
dc.titleEvaluation of hs-CRP and visseral adiposity index in patients with policystic ovary syndrome by clinical and laboratory findingsen_US
dc.typeArticleen_US

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