Synthesis, characterization and antioxidant activity of chitosan-chromone derivatives

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dc.authoridBeyazit, Neslihan/0000-0002-5722-2400
dc.authoridDEMETGUL, CAHIT/0000-0003-1559-7279
dc.contributor.authorDemetgul, Cahit
dc.contributor.authorBeyazit, Neslihan
dc.date.accessioned2024-09-18T20:08:20Z
dc.date.available2024-09-18T20:08:20Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIn this study, a new chromone-functionalized chitosan Schiff base and its cross-linked derivative were synthesized and characterized by FT-IR, UV-vis, C-13 CP/MAS solid-state NMR, TGA, XRD-powder and SEM measurements and elemental analysis data. Degrees of substitution (DS) were determined from the elemental analysis by using the C/N ratios. The in vitro antioxidant activity of high molecular chitosan and its chromone derivatives was evaluated as radical scavengers against 1,1-diphenyl-2-picrylhydrazyl radicals (DPPH%). The results showed that both of the chitosan-chromone derivatives have good antioxidant potential which might be due to the phenolic group introduced after chemical modification of chitosan with a chromone derivative. Chromone-chitosan Schiff base (CSCH) had a better ability to scavenging DPPH radical (IC50, 0.88 mg/mL) than that of its cross-linked derivative (CSCH-TP) obtained by using terephthalaldehyde (IC50, 1.32 mg/mL).en_US
dc.identifier.doi10.1016/j.carbpol.2017.11.074
dc.identifier.endpage817en_US
dc.identifier.issn0144-8617
dc.identifier.issn1879-1344
dc.identifier.pmid29254040en_US
dc.identifier.scopus2-s2.0-85035221006en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage812en_US
dc.identifier.urihttps://doi.org/10.1016/j.carbpol.2017.11.074
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8783
dc.identifier.volume181en_US
dc.identifier.wosWOS:000418661000094en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofCarbohydrate Polymersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChitosan derivativesen_US
dc.subjectChromoneen_US
dc.subjectTerephthalaldehydeen_US
dc.subjectAntioxidant activityen_US
dc.titleSynthesis, characterization and antioxidant activity of chitosan-chromone derivativesen_US
dc.typeArticleen_US

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