An evaluation with shear wave elastography of kidney elasticity in patients with familial Mediterranean fever

dc.authoridOzturk KELES, Fatma/0000-0003-3430-1162
dc.authoridSeyfettin, Ayca/0000-0002-8540-9432
dc.authoridDIRICAN, EMRE/0000-0003-3550-1326
dc.contributor.authorKayali, Alperen
dc.contributor.authorKeles, Fatma Ozturk
dc.contributor.authorSeyfettin, Ayca
dc.contributor.authorDirican, Emre
dc.contributor.authorCelik, Muhammed Murat
dc.date.accessioned2024-09-18T20:25:10Z
dc.date.available2024-09-18T20:25:10Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose To investigate the changes in kidney elasticity in patients with familial Mediterranean fever using the non-invasive diagnostic method of shear wave elastography (SWE). Methods The kidney elasticity of 35 FMF patients and 23 healthy control subjects was evaluated with SWE. The relationships were evaluated of the SWE values with eGFR, microproteinuria, FMF severity score, number of attacks per month, and colchicine doses of the FMF patients. Results The kidney stiffness and velocity values of the FMF patients were found to be higher than those of the control group (p < 0.001). A negative correlation was found between the renal stiffness and velocity values and the colchicine dose (r = -0.48, p = 0.004, and r = -0.50, p = 0.003, respectively). Conclusion The results of the current study demonstrated that the SWE values of the FMF patients were significantly higher than those of the control group. SWE can be used as an alternative method in the follow up of FMF patients. In addition, a negative correlation was determined between the colchicine dose and renal stiffness. This suggests that SWE values could be used in the adjustments of colchicine doses. However, there is a need for further studies with greater numbers of patients to support this hypothesis.en_US
dc.identifier.doi10.1002/jcu.23375
dc.identifier.endpage183en_US
dc.identifier.issn0091-2751
dc.identifier.issn1097-0096
dc.identifier.issue1en_US
dc.identifier.pmid36251543en_US
dc.identifier.scopus2-s2.0-85140035018en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage177en_US
dc.identifier.urihttps://doi.org/10.1002/jcu.23375
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10121
dc.identifier.volume51en_US
dc.identifier.wosWOS:000868799900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Ultrasounden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFMFen_US
dc.subjectkidneyen_US
dc.subjectshear wave elastographyen_US
dc.subjectstiffnessen_US
dc.subjectultrasounden_US
dc.titleAn evaluation with shear wave elastography of kidney elasticity in patients with familial Mediterranean feveren_US
dc.typeArticleen_US

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