Platelet to Lymphocyte Ratio in Cardiovascular Diseases: A Systematic Review

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dc.contributor.authorKurtul, Alparslan
dc.contributor.authorOrnek, Ender
dc.date.accessioned2024-09-18T20:54:18Z
dc.date.available2024-09-18T20:54:18Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe platelet to lymphocyte ratio (PLR) is an integrated reflection of 2 opposite thrombotic/inflammatory pathways that are easily calculated from a complete blood count. The PLR initially served as a systemic inflammatory biomarker to predict the prognosis of neoplastic diseases. In recent years, the PLR has been used as a prognostic marker in cardiovascular (CV) conditions. In this review, we consider the evidence regarding the association of the PLR with CV disease (CVD) and its possible use as a prognostic marker of CVD. The role of PLR has been investigated in CV conditions in several studies. We assessed clinical trials using PubMed, EMBASE, and Web of Science (up to April 18, 2018) to evaluate the association between PLR and mortality/major adverse cardiac events in these conditions. Most of these studies reported significant relationships between a high PLR and diverse outcomes. In conclusion, we suggest that PLR is a cheap and easily available systemic inflammatory marker that can predict distinct outcomes in different types of CVD.en_US
dc.identifier.doi10.1177/0003319719845186
dc.identifier.endpage818en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue9en_US
dc.identifier.pmid31030530en_US
dc.identifier.scopus2-s2.0-85065222996en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage802en_US
dc.identifier.urihttps://doi.org/10.1177/0003319719845186
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11728
dc.identifier.volume70en_US
dc.identifier.wosWOS:000483822200004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectplatelet to lymphocyte ratioen_US
dc.subjectinflammationen_US
dc.subjectthrombosisen_US
dc.subjectcardiovascular eventsen_US
dc.titlePlatelet to Lymphocyte Ratio in Cardiovascular Diseases: A Systematic Reviewen_US
dc.typeReview Articleen_US

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