INTRACRANIAL HEMORRHAGE DUE TO VITAMIN K DEFICIENCY IN INFANTS: A CLINICAL STUDY

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dc.contributor.authorYilmaz, C.
dc.contributor.authorYuca, S. A.
dc.contributor.authorYilmaz, N.
dc.contributor.authorBektas, M. S.
dc.contributor.authorCaksen, H.
dc.date.accessioned2024-09-18T20:28:07Z
dc.date.available2024-09-18T20:28:07Z
dc.date.issued2009
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe hospital records of 30 infants with a diagnosis of intracranial hemorrhage (ICH) due to late onset of vitamin K deficiency, seen during a 5-year period (2001-2005) were retrospectively evaluated. Signs and symptoms of the patients were convulsions (80%), poor sucking (50%), irritability (40%), vomiting (47%), acute diarrhea (33%), and fever (40%). On physical examination there were bulging or full fontanel in 19 patients (63%), collapsed fontanel in one (3%), diminished or absent neonatal reflexes in 11 (37%), pallor in 14 (47%), and cyanosis in one (3%) patient. Gastrointestinal disorder, skin hemorrhagic findings, and epistaxis each were noted in two (7%) patients. All the infants had prolonged prothrombin time (PT) and seven had prolonged activated partial thromboplastin time (APTT), both of which were corrected by the administration of vitamin K. All the infants had ICH, with the most common being intraparenchymal hemorrhage, followed by multiple type ICH (27%). Neurosurgical intervention was performed in five patients (17%). The overall case fatality rate was 33%. In conclusion, we would like to stress that ICH due to vitamin K deficiency in infants is still an important health problem in Turkey resulting in high mortality rate.en_US
dc.identifier.doi10.3109/00207450903170437
dc.identifier.endpage2256en_US
dc.identifier.issn0020-7454
dc.identifier.issn1563-5279
dc.identifier.issue12en_US
dc.identifier.pmid19916853en_US
dc.identifier.scopus2-s2.0-70450210965en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2250en_US
dc.identifier.urihttps://doi.org/10.3109/00207450903170437
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10742
dc.identifier.volume119en_US
dc.identifier.wosWOS:000271275900009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal of Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectinfanten_US
dc.subjectintracranial hemorrhageen_US
dc.subjectvitamin Ken_US
dc.titleINTRACRANIAL HEMORRHAGE DUE TO VITAMIN K DEFICIENCY IN INFANTS: A CLINICAL STUDYen_US
dc.typeArticleen_US

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