Evaluation of ovarian reserve in Hashimoto's thyroiditis

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dc.authoridHatipoglu, Esra/0000-0001-8361-8866
dc.authoridAcikgoz, Abdullah Serdar/0000-0001-9355-7753
dc.authoridTUTEN, ABDULLAH/0000-0002-8495-6426
dc.authoridOncul, Mahmut/0000-0002-9634-3651
dc.contributor.authorTuten, Abdullah
dc.contributor.authorHatipoglu, Esra
dc.contributor.authorOncul, Mahmut
dc.contributor.authorImamoglu, Metehan
dc.contributor.authorAcikgoz, Abdullah Serdar
dc.contributor.authorYilmaz, Nevin
dc.contributor.authorOzcil, Mustafa Dogan
dc.date.accessioned2024-09-18T19:50:25Z
dc.date.available2024-09-18T19:50:25Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractHuman ovary is commonly the target of an autoimmune attack in cases of organ-or non-organ-specific autoimmune disorders. Hashimoto's thyroiditis (HT) is likely to be associated with ovarian dysfunction and diminished ovarian reserve. In this study, we aimed to evaluate the possible negative association between this significantly prevalent autoimmune disease and the ovarian reserve. Thirty-two premenopausal women with primary hypothyroidism, who under replacement therapy with thyroxine were recruited. Forty-nine healthy female subjects who had normal anti-thyroid antibody levels and were comparable with the HT group in terms of age and BMI values, comprised the control group. There was no statistically significant difference between the study and the control patients in terms of antral follicle count. Serum anti-Mullerian hormone (AMH) levels were significantly higher in woman with HT compared to the control group. The results of this study found no impairment in ovarian reserve parameters of patients with HT. Interestingly, the results revealed a significant increase in serum AMH levels of the patients with HT compared to controls. Hashimoto's thyroiditis may share a common etiologic linkage with polycystic ovary syndrome; therefore, leading to elevated serum AMH levels, which we are currently unable to define elaborately.en_US
dc.identifier.doi10.3109/09513590.2014.926324
dc.identifier.endpage711en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue10en_US
dc.identifier.pmid24905723en_US
dc.identifier.scopus2-s2.0-84907913671en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage708en_US
dc.identifier.urihttps://doi.org/10.3109/09513590.2014.926324
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7434
dc.identifier.volume30en_US
dc.identifier.wosWOS:000342554700010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAFCen_US
dc.subjectAMHen_US
dc.subjectHashimoto's thyroiditisen_US
dc.subjectovarian reserveen_US
dc.subjectPCOSen_US
dc.titleEvaluation of ovarian reserve in Hashimoto's thyroiditisen_US
dc.typeArticleen_US

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