Assessment of inflammatory markers in otosclerosis patients

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dc.authoridSARAC, ELIF TUGBA/0000-0001-6058-4966
dc.authoridGulmez, Mehmet Ihsan/0000-0003-0462-6353
dc.contributor.authorArli, Cengiz
dc.contributor.authorGulmez, Ihsan
dc.contributor.authorSarac, Elif Tugba
dc.contributor.authorOkuyucu, Semsettin
dc.date.accessioned2024-09-18T20:53:00Z
dc.date.available2024-09-18T20:53:00Z
dc.date.issued2020
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction: Otosclerosis is an idiopathic disease characterized by new bone formation in foci of the human otic capsule. It is more common in Caucasian populations; affecting females twice as often as males. Its etiopathogenesis has not yet been fully elucidated. Objective: The aim of this study was to investigate the relationship between otosclerosis and white blood cell and thrombocyte counts, mean platelet volume, neutrophil lymphocyte ratio, and the platelet lymphocyte ratio. Methods: This retrospective case-control study was conducted in the outpatient clinic Mustafa Kemal University, in the department of otolaryngology, between 2015 and 2018. A total of 30 patients with an established diagnosis of otosclerosis were compared to a control group of 30 healthy subjects, matched for age, gender and body mass index. The white blood cell, thrombocyte, mean platelet volume, neutrophil lymphocyte ratio and platelet lymphocyte ratio values were calculated for all participants. Results: There was no statistically significant difference between the groups with respect to age, gender, or body mass index, or for the mean neutrophil lymphocyte ratio, platelet lymphocyte ratio, white blood cell, or thrombocyte values (p> 0.05). A statistically significant difference was determined between the groups for the mean platelet volume values. The mean platelet volume values were lower in the otosclerotic patients (p = 0.047). Conclusion: These results show that neutrophil lymphocyte ratio, platelet lymphocyte ratio, white blood cell and thrombocytes should not be used to predict otosclerosis, but suggest that mean platelet volume may be a negative predictive marker. (C) 2019 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda.en_US
dc.identifier.doi10.1016/j.bjorl.2018.12.014
dc.identifier.endpage460en_US
dc.identifier.issn1808-8694
dc.identifier.issn1808-8686
dc.identifier.issue4en_US
dc.identifier.pmid30926454en_US
dc.identifier.scopus2-s2.0-85063283609en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage456en_US
dc.identifier.urihttps://doi.org/10.1016/j.bjorl.2018.12.014
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11531
dc.identifier.volume86en_US
dc.identifier.wosWOS:000557456100010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isopten_US
dc.publisherAssoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacialen_US
dc.relation.ispartofBrazilian Journal of Otorhinolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOtosclerosisen_US
dc.subjectNeutrophil lymphocyte ratioen_US
dc.subjectPlatelet lymphocyte ratioen_US
dc.subjectMean platelet volumeen_US
dc.subjectInflammatory markersen_US
dc.titleAssessment of inflammatory markers in otosclerosis patientsen_US
dc.typeArticleen_US

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