Comparison of the effects of methylprednisolone and dexamethasone on preventing vomiting after tonsillectomy in children
[ N/A ]
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: In the present study we aimed to compare the effects of methyl perdnisolone, an intermediate acting glucocorticoid, on preventing vomiting after tonsillectomy or adenoidectomy with that of dexamethasone. Material and Methods: A total of 110 patients going under tonsillectomy or adenoidectomy were included to the study. Patients were randomized into two groups. Group D was administered dexamethasone 0.5 mg/kg (max 8 mg) intravenously following general anesthesia before surgery was started whereas group M was administered methyl prednisolone 2.5 mg kg-1 (max 40 mg). Patients were assessed for 2 hours in the post-op room (early stage) and the following 24 hours (late stage) and incidence of vomiting, the first analgesic administration time, cheops pain score (at 15 min, 1 hour, 2hrs and 4 hrs after surgery) and oral intake quality were recorded. Results: Demographic data did not differ between groups. There was not statistically significant difference in the incidence of early stage or late stage vomiting between the two groups (p>0.05). We did not find statistically significant difference in the time of first analgesic administration between the two group (p>0.05). Side effects were similar in the two groups. Conclusion: We suggest that prednisolone is as effective as dexamethasone in preventing vomiting after tonsillectomy without causing further side effects and that it could be used as an alternative agent when latter is unavailable.
Açıklama
Anahtar Kelimeler
Dexamethasone, Methyl prednisolone, Postoperative vomiting, Tonsillectomy
Kaynak
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
36
Sayı
5
