Left ventricular wall function abnormalities in patients with ankylosing spondylitis evaluated by gated myocardial perfusion scintigraphy

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dc.contributor.authorYalcin, H.
dc.contributor.authorGuler, H.
dc.contributor.authorGunay, E.
dc.contributor.authorYeral, N.
dc.contributor.authorTurhanoglu, A.
dc.contributor.authorBolac, E.
dc.contributor.authorYalcin, F.
dc.date.accessioned2024-09-18T20:59:17Z
dc.date.available2024-09-18T20:59:17Z
dc.date.issued2011
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: Ankylosing spondilitis (AS) is a chronic inflammatory disease with prominent inflammation in joints and extraarticular organs. AS patients have approximately two times more risk of mortality than the normal population. One reason for this increase in mortality is increased cardiovascular risk. In this study, we have aimed to evaluate myocardial perfusion and left ventricular function using Tc-99m-MIBI gated myocardial perfusion single photon emission computed tomography (SPECT). Material and methods: The study group consisted of 28 AS patients (19 men, 9 women), and mean age 39.46 +/- 10.98 years. All patients underwent Tc-99m-MIBI gated myocardial perfusion SPECT with the same day protocol. Results: We detected various risk factors including smoking habits in 12, family history of cardiovascular disease in 12, hypertension in 3, hyperlipidemia in 9 patients. We performed a myocardial perfusion SPECT for each patient and found normal perfusion pattern in SPECT images. Out of 28 patients, eight patients had normal perfusion but wall motion abnormalities. Conclusion: We detected that myocardial perfusion is preserved in the patients with AS. However, left ventricular wall motion abnormalities are seen. We concluded that ankylosing spondylitis may be associated with microvascular dysfunction and gated myocardial perfusion scintigraphy could be valuable in AS patients for the evaluation of LV function even if the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score are low and the disease duration shorter. (C) 2010 Elsevier Espana, S.L. and SEMNIM. All rights reserved.en_US
dc.identifier.doi10.1016/j.remn.2010.12.002
dc.identifier.endpage296en_US
dc.identifier.issn0212-6982
dc.identifier.issn1578-200X
dc.identifier.issue5en_US
dc.identifier.pmid21435747en_US
dc.identifier.scopus2-s2.0-80051940064en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage292en_US
dc.identifier.urihttps://doi.org/10.1016/j.remn.2010.12.002
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12499
dc.identifier.volume30en_US
dc.identifier.wosWOS:000294659400005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofRevista Espanola De Medicina Nuclearen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTc-99m-MIBIen_US
dc.subjectGated myocardial perfusion SPECTen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectWall motionen_US
dc.subjectAnkylosing spondilitisen_US
dc.titleLeft ventricular wall function abnormalities in patients with ankylosing spondylitis evaluated by gated myocardial perfusion scintigraphyen_US
dc.typeArticleen_US

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