Antifungal activity of several root canal sealers against Candida albicans

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dc.contributor.authorOzcan, Erhan
dc.contributor.authorYula, Erkan
dc.contributor.authorArslanoglu, Zeki
dc.contributor.authorInci, Melek
dc.date.accessioned2024-09-18T19:52:31Z
dc.date.available2024-09-18T19:52:31Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective. The purpose of this in vitro study was to evaluate the antifungal activity of several root canal sealers (iRoot SP, MTA Fillapex and GuttaFlow) against Candida albicans and compare them to that of AH Plus Jet. Materials and methods. A10 mu L fungi in suspension was allowed to directly contact the sealers, which were freshly mixed or allowed to set for 1 or 7 days. Fresh media was then added and survival of fungi was determined by using 10-fold serial dilution and inoculated onto agar plates. After incubation for 48 h, colony-forming units (CFU) were calculated and their log(10) values converted. The data were analyzed using ANOVA and Tukey tests (alpha = 0.05). Results. Freshly mixed AH Plus Jet totally inhibited the growth of fungi and showed the highest antifungal activity. GuttaFlow did not show any significant antifungal activity at all times. Freshly mixed iRoot SP and MTA Fillapex were found to be antifungal. Statistical differences were found between freshly mixed and set samples (p < 0.05) in favor of the former, except GuttaFlow. No statistically significant differences were found among the tested sealers at the 1 and 7-day samples (p > 0.05). Conclusions. Fresh AH Plus Jet had very potent antifungal activity. All sealers, except GuttaFlow, exhibited antifungal activity when freshly mixed.en_US
dc.identifier.doi10.3109/00016357.2013.771405
dc.identifier.endpage1485en_US
dc.identifier.issn0001-6357
dc.identifier.issn1502-3850
dc.identifier.issue6en_US
dc.identifier.pmid24180589en_US
dc.identifier.scopus2-s2.0-84887232376en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1481en_US
dc.identifier.urihttps://doi.org/10.3109/00016357.2013.771405
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7483
dc.identifier.volume71en_US
dc.identifier.wosWOS:000326678700020en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Odontologica Scandinavicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAH Plus Jeten_US
dc.subjectantifungal activityen_US
dc.subjectGuttaFlowen_US
dc.subjectiRoot SPen_US
dc.subjectMTA Fillapexen_US
dc.titleAntifungal activity of several root canal sealers against Candida albicansen_US
dc.typeArticleen_US

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