Evaluation of total oxidative stress and total antioxidant status in cows with natural bovine herpesvirus-1 infection

Basit Öğe Kaydı
dc.contributor.authorDurgut, R.
dc.contributor.authorAtaseven, V. S.
dc.contributor.authorSagkan-Ozturk, A.
dc.contributor.authorOzturk, O. H.
dc.date.accessioned2024-09-18T20:02:32Z
dc.date.available2024-09-18T20:02:32Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractViruses, including herpes viruses, can alter oxidative balance by either increasing the formation of free radicals or inhibiting synthesis of enzymes involved in oxidative defense within host cells. This study examined the occurrence of oxidative and antioxidative balance in cows naturally infected with bovine herpesvirus type 1 (BHV-1) under field conditions. Clinical history indicated that cows had been sick and showed mild to severe respiratory signs, characterized by dullness, coughing, and lacrimation, and a high febrile response. All samples obtained from the infected animals during clinical examination were confirmed as positive for bovine herpesvirus type 1 by PCR. Control cows showed no clinical abnormalities and PCR results were negative. Total antioxidative status, total oxidant status, oxidative stress index, and some biochemical parameters were measured. The level of total antioxidative status was significantly lower in infected animals, compared with the healthy control group (P = 0.025). However, there was no statistically significant difference between the 2 groups for total oxidant status and oxidative stress index levels. Furthermore, there was a significant decrease in the infected groups, with respect to concentrations of alkaline phosphatase, alanine transferase, gamma glutamyl transferase, monocyte, and erythrocyte (P < 0.05). On the other hand, aspartate aminotransferase and creatinine kinase concentrations significantly increased in the cows infected with BHV-1. In conclusion, the data obtained hereby explained that animals with infected BHV-1 seemed to have more oxidative stress and low antioxidant defense. Moreover, future research conductance is needed on antioxidative and oxidative balance to understand pathophysiology of BHV-1 infections.en_US
dc.identifier.doi10.2527/jas.2012-5516
dc.identifier.endpage3412en_US
dc.identifier.issn0021-8812
dc.identifier.issn1525-3163
dc.identifier.issue7en_US
dc.identifier.pmid23798525en_US
dc.identifier.scopus2-s2.0-84879340912en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3408en_US
dc.identifier.urihttps://doi.org/10.2527/jas.2012-5516
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7839
dc.identifier.volume91en_US
dc.identifier.wosWOS:000320856200043en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Press Incen_US
dc.relation.ispartofJournal of Animal Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantioxidative statusen_US
dc.subjectbovine herpesvirus-1en_US
dc.subjectoxidative statusen_US
dc.subjectrespiratory diseaseen_US
dc.titleEvaluation of total oxidative stress and total antioxidant status in cows with natural bovine herpesvirus-1 infectionen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
7839.pdf
Boyut:
694.52 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu