A Rare Case of Vulvar Langerhans Cell Histiocytosis and Review of the Literature

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dc.authoridAkay, Bengu Nisa/0000-0002-4896-1666
dc.contributor.authorBalci, Didem Didar
dc.contributor.authorKundakci, Nihal
dc.contributor.authorGurel, Mehmet Salih
dc.contributor.authorYaldiz, Mehmet
dc.contributor.authorDogramaci, Cigdem Asena
dc.contributor.authorAkay, Bengu Nisa
dc.date.accessioned2024-09-18T20:29:29Z
dc.date.available2024-09-18T20:29:29Z
dc.date.issued2009
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractLangerhans cell histiocytosis (LCH) of the vulva is rare. A 32 year-old woman presented with a two year history of non-healing vulvar ulceration and a nine month history of ulcerative nodular lesion in the left inguinal region. Biopsy results of the vulva and inguinal lesions were consistent with LCH. Screening of the body systems revealed hepatosplenomegaly, iliac, inguinal, paraaortic lymph nodes and lung involvement. She was treated with systemic steroid, resulting in complete improvement of vulvar lesion. She also underwent a local excision of left inguinal lesion. Three months later, we found a lesion on her left inguinal region that was consistent with a recurrence and enlargement in the lymph nodes. Therefore, high dose systemic steroid therapy and then a 12-session radyotherapy were given. After the treatment, a complete improvement was obtained. A 1-year of systemic methotrexate therapy was recommended to prevent recurrence of the disease. In women with vulvar ulcer, LCH should be considered in the differential diagnosis.en_US
dc.identifier.endpage103en_US
dc.identifier.issn1307-7635
dc.identifier.issn1308-5255
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-77953398571en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage97en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10877
dc.identifier.volume3en_US
dc.identifier.wosWOS:000420845000005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurk Dermatoloji Dergisi-Turkish Journal of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLangerhans cell histiocytosisen_US
dc.subjectvulvaen_US
dc.subjectulceren_US
dc.titleA Rare Case of Vulvar Langerhans Cell Histiocytosis and Review of the Literatureen_US
dc.typeArticleen_US

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