The effects of mobile phones on apoptosis in cerebral tissue: an experimental study on rats

dc.authoridYILMAZ, Atilla/0000-0002-1081-3545
dc.authoridSefil, Fatih/0000-0001-5534-7448
dc.contributor.authorYilmaz, A.
dc.contributor.authorYilmaz, N.
dc.contributor.authorSerarslan, Y.
dc.contributor.authorAras, M.
dc.contributor.authorAltas, M.
dc.contributor.authorOzgur, T.
dc.contributor.authorSefil, F.
dc.date.accessioned2024-09-18T20:02:33Z
dc.date.available2024-09-18T20:02:33Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractINTRODUCTION: The concern about mobile phone effects is increasing as the number of users increasing too. Different studies have different results, so this topic is still open to discussion. Aim of this report was to investigate the effects of the mobile phones on the Bcl-2 gene and p53 proteins in rat brains. MATERIALS AND METHODS: In the study group of 10 rats; mobile phones that spread EMW at a frequency between 1900-2100 MHz and Specific Absorption Rate range between 0.005 W/kg and 0.288 W/kg (Dialing mode), 0.004 W/kg and 0.029 W/kg (Calling mode) were attached to rat ears for simulating usage in daily life for 7 times a day during 5 minutes (3 seconds dialing mode, 4 minutes and 47 seconds of calling mode) for a four week period. Sham group (n=10) rats were only immobilized without EMW exposure. Another group of rats (n=10) were counted as control without any application. immunohistopathological examination was performed for p53 and Bcl-2 expression. RESULTS: Immunohistopathological examinations revealed that the samples in the study group had more p53 and Bcl-2 positive stained cells and they were stained denser. In both evaluations, these differences between the study and control group were found statistically significant (p < 0.003); In Bcl-2 evaluation statistically significant difference was found between study and sham group to (p < 0.005); however, the p53 evaluation between the study and the sham group did not show any statistically significant difference (p > 0.005). CONCLUSIONS: Our results showed that the electro-magnetic waves emitted by the mobile phones may have effect on apoptosis. Besides, obtained data revealed that more realistic application of mobile phones during experiments is more important as expected.en_US
dc.description.sponsorshipMustafa Kemal University Scientific Research Projects Coordination Unit [401]en_US
dc.description.sponsorshipThis study was funded in full by Mustafa Kemal University Scientific Research Projects Coordination Unit, grant number 401.en_US
dc.identifier.endpage1000en_US
dc.identifier.issn1128-3602
dc.identifier.issue7en_US
dc.identifier.pmid24763879en_US
dc.identifier.scopus2-s2.0-84902139116en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage992en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7863
dc.identifier.volume18en_US
dc.identifier.wosWOS:000341969400009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApoptosisen_US
dc.subjectBcl-2en_US
dc.subjectBrainen_US
dc.subjectCellular Phoneen_US
dc.subjectElectromagnetic Wavesen_US
dc.subjectGSMen_US
dc.subjectHistopathologyen_US
dc.subjectMobile Phoneen_US
dc.subjectP53en_US
dc.subjectRaten_US
dc.titleThe effects of mobile phones on apoptosis in cerebral tissue: an experimental study on ratsen_US
dc.typeArticleen_US

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