The Evaluation of the Seroprevalence of HBV and HCV Infections in Patients with Hemodialysis in Hatay City and the Assessment of Antibody Response to Hepatitis B Vaccination
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
Galenos Publ House
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Patients with end stage renal disease (ESRD) being treated with hemodialysis (HD) usually require frequent blood transfusions and hospitalizations. Therefore, they are at high risk of hepatitis. Because of infection control programs and regular vaccinations in dialysis centers, a decrease in the prevalence of hepatitis due to HBV and HCV infections is observed in these units. The present study aimed to investigate the seroprevalence of HBV and HCV infections in patients with HD in dialysis centers of Hatay city and to assess antibody response to hepatitis B vaccination. A total of 801 HD patients were included in the study between January 01 and December 31, 2009 from seven HD centers. Data were obtained from the files retrospectively. HBsAg, anti-HBs and anti-HCV seropositivity of the patient's samples were analyzed by enzyme immunoassay method. Of the 801 HD patients included, 480 (59.9%) were male and 321 (40.1%) were female. The mean age of the patients was 58.2 +/- 14.9 years (range, 10-98 years). HBsAg was positive in 29 (3.6%) patients and anti-HCV was positive in 76 (9.5%) patients. Five (0.6%) patients had both HBsAg and anti-HCV positivity. Of the 712 patients whose anti-HBs data were available, 578 (72.2%) patients were anti-HBs positive, whereas 134 (16.7%) were not. In the present study, although a lower hepatitis B and C prevalence was found in Hatay city compared with the previous studies conducted in Turkey, our results were similar reported for European countries. However, viral hepatitis is still an important health problem in HD patients. Infection control programs, vaccination, the education of the patients and health staff may decrease the incidence ofnewinfections.
Description
Keywords
Hemodialysis, hepatitis B virus, hepatitis C virus, seroprevalence, vaccination
Journal or Series
Viral Hepatit Dergisi-Viral Hepatitis Journal
WoS Q Value
N/A
Scopus Q Value
Volume
16
Issue
2
