Induction of labor in great grandmultipara with misoprostol

dc.contributor.authorZeteroglu, S
dc.contributor.authorSahin, HG
dc.contributor.authorSahin, HA
dc.date.accessioned2024-09-18T20:28:07Z
dc.date.available2024-09-18T20:28:07Z
dc.date.issued2006
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: To compare the efficacy and complications of intravaginal misoprostol application with oxytocin infusion for induction of labor in great grandmultiparous pregnancies with a Bishop score of <6. Study design: Sixty-four great grandmultiparous (delivering the tenth, or greater, infant) pregnant patients with a Bishop score of <6 were randomized in two groups with 32 patients receiving 50 mu g intravaginal misoprostol four times with 4 It intervals, and 32 patients receiving oxytocin infusion for induction of labor starting from 2 mIU/min, increasing it every 30 min with 2 mIU/min increments up to maximum of 40 mIU/min. The time from induction to delivery, the route of delivery, fetal outcome and maternal complications were recorded. Statistical analyses were performed using Mann-Whitney U-test, Chi-Square test and hypothesis test about differences for two proportions (t-test) to determine differences between the two groups. P <= 0.05 was considered significant. Result: The mean time from induction to delivery was 9.91 +/- 4.30 and 10.88 +/- 4.72 h in the misoprostol and oxytocin administered group, respectively, with no significant difference between the groups. The rate of vaginal delivery was 84.4 and 87.5% in the misoprostol and oxytocin administered group, respectively, with no significant difference between the groups (P = 0.72). The rates of placental abruption and postpartum hemorrhage were similar in both groups and no case of uterine rupture occurred. The 1 and 5 min mean Apgar scores were 6.91 +/- 1.57-8.88 +/- 1.39 and 7.22 +/- 1.24-9.06 +/- 0.84 in the misoprostol and oxytocin administered group with no significant differences between the groups (P = 0.38 and 0.51). No case of asphyxia was present. The rate of admission to neonatal intensive care unit was higher in the misoprostol administered group, but the difference was not significant. Conclusion: Intravaginal misoprostol is an alternative method to oxytocin in induction of labor in great grandmultiparous pregnant women with low Bishop scores, as it is effective, cheap and easy to use. Safety about rare complications and neonatal morbidity needs clarifications with further studies. (C) 2005 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejogrb.2005.07.012
dc.identifier.endpage32en_US
dc.identifier.issn0301-2115
dc.identifier.issue1en_US
dc.identifier.pmid16129547en_US
dc.identifier.scopus2-s2.0-33748054288en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage27en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2005.07.012
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10740
dc.identifier.volume126en_US
dc.identifier.wosWOS:000238005400005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofEuropean Journal of Obstetrics Gynecology and Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectinduction of laboren_US
dc.subjectgreat grandmultiparityen_US
dc.subjectmisoprostolen_US
dc.subjectoxytocinen_US
dc.titleInduction of labor in great grandmultipara with misoprostolen_US
dc.typeArticleen_US

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