Evaluation of the levels of homocysteine, troponin i, and nitric oxide in lambs with subclinical white muscle disease

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dc.authorscopusid55935021100
dc.authorscopusid12243148200
dc.authorscopusid35618550600
dc.authorscopusid12243015300
dc.contributor.authorKozat, Süleyman
dc.contributor.authorAltu?, Nuri
dc.contributor.authorYüksek, Nazmi
dc.contributor.authorÖzkan, Cumali
dc.date.accessioned2024-09-19T15:48:34Z
dc.date.available2024-09-19T15:48:34Z
dc.date.issued2011
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractWhite muscle disease (WMD) or Nutritional myodegeneration disease (NMD) is a degenerative disease of the cardiac and skeletal muscles. The level of serum activity of Plasma homocysteine (Hcy), cardiac troponin I (cTn I), Nitric oxide (NO) were investigated in lambs with subclinical NMD in this study. Ten healthy lambs and twenty lambs with subclinical NMD were used in this study. The blood samples were firstly taken at the onset of the disease and then 3 and 10 days after treatment in NMD, and taken once control group. The values of serum activity of creatin kinase (CK), aspartate aminotranferase (AST), alanine aminotranferase (ALT), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were measured with autoanalyzer. Plasma concentration of Hcy, serum cTn I, and levels of NO were determined with ELISA method and value of activity erythrocyte glutathione peroxidase (GSH-Px) was measured with spectrophotometer. Before treatment, values of plasma Hcy, serum NO, cTn I, AST, ALT, ALP, CK, and LDH in lambs with NMD were higher than those of healthy ones (P<0.001), while GSH-Px activity of lambs with NMD are lower than those of healthy (P<0.001). After ten days of treatment, there were no significant diff erences between treated lambs with NMD and healthy lambs. Nutritional myodegeneration in lambs is associated with increased levels of Hcy, cTn I, and NO. Increased levels of Hcy, cTn I, and NO may be a result of selenium deficiency causing myocardial disorder in NMD lambs.en_US
dc.identifier.endpage444en_US
dc.identifier.issn1300-6045
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-79955766741en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage441en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15160
dc.identifier.volume17en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherVeteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHomocysteineen_US
dc.subjectLamben_US
dc.subjectNitric oxideen_US
dc.subjectNutritional Myodegenerationen_US
dc.subjectTroponin Ien_US
dc.titleEvaluation of the levels of homocysteine, troponin i, and nitric oxide in lambs with subclinical white muscle diseaseen_US
dc.title.alternativeSubklinik beyaz kas hastalıklı kuzularda homosistein, troponin i ve nitrik oksit düzeylerinin de?erlendirilmesien_US
dc.typeArticleen_US

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